DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sry-beta and Zkscan1

DIOPT Version :9

Sequence 1:NP_001303451.1 Gene:Sry-beta / 43570 FlyBaseID:FBgn0003511 Length:356 Species:Drosophila melanogaster
Sequence 2:NP_001020931.1 Gene:Zkscan1 / 498160 RGDID:1560616 Length:562 Species:Rattus norvegicus


Alignment Length:345 Identity:89/345 - (25%)
Similarity:140/345 - (40%) Gaps:49/345 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 KIINQRLELLPNSAACRDCLEYLFNYDRLVRNLSQVQRQIADALLGCR-----QVEGKAETKQQA 103
            ||.:..:.|:.....|::......|.|....||..|..|.::...|..     :|:|.:.:..:.
  Rat   227 KIEDMAVSLILEEWGCQNLARRNLNRDSRQMNLGTVFSQGSENRNGSESTSKAEVKGDSTSHGEI 291

  Fly   104 AKRARVQVPAFKIVQATAL----KEPERQPGEEDEC--------------EEFMKE--EMLDEEF 148
            |.|.:.:....:..|...:    |.||.:.|:|.:.              |...:|  :.|...|
  Rat   292 AGRFQKEFGEKREQQGRVIERQQKNPEEKTGKEKKAPGPPTAKEKKPTTGERGPREKGKGLGRSF 356

  Fly   149 QFSEPDDSMPSSEEEFFTETTEIP-------CHICGEMFSSQEVLERHIKADTCQKSEQATCNVC 206
            ..|...::.|.          |||       |..||:.|:....|.||....|.:|..:  ||.|
  Rat   357 SLSANFNNTPE----------EIPSGAKTHRCDECGKCFTRSSSLIRHKIIHTGEKPYE--CNEC 409

  Fly   207 GLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWL 271
            |.....:..|.||..:|.|:...||..|.|.|||..|::.|..:|..:|.|:|::||:.||.|..
  Rat   410 GKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSD 474

  Fly   272 MYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRV 336
            :..|...|..|: ...|..|.:.|........|.|.|..::| |.|..|.|:|....||.:|.|:
  Rat   475 LTKHQRIHTGEK-PYECSECGKAFNRNSYLILHRRIHTREKP-YKCTKCGKAFTRSSTLTLHHRI 537

  Fly   337 HQPVEKPESAEAKEATVTFF 356
            |   .:..::|...|::..|
  Rat   538 H---ARERASEYSPASLDTF 554

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sry-betaNP_001303451.1 C2H2 Zn finger 203..223 CDD:275368 7/19 (37%)
C2H2 Zn finger 231..251 CDD:275368 8/19 (42%)
C2H2 Zn finger 259..308 CDD:275368 14/48 (29%)
C2H2 Zn finger 288..303 CDD:275370 3/14 (21%)
zf-C2H2 315..337 CDD:278523 9/21 (43%)
C2H2 Zn finger 317..337 CDD:275368 8/19 (42%)
Zkscan1NP_001020931.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 31..50
SCAN 52..162 CDD:128708
SCAN 52..129 CDD:280241
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 164..187
KRAB 226..264 CDD:279668 9/36 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 261..372 22/120 (18%)
C2H2 Zn finger 353..370 CDD:275368 4/26 (15%)
COG5048 <355..536 CDD:227381 60/194 (31%)
zf-C2H2 376..398 CDD:278523 7/21 (33%)
C2H2 Zn finger 378..398 CDD:275368 7/19 (37%)
zf-H2C2_2 390..414 CDD:290200 9/25 (36%)
C2H2 Zn finger 406..426 CDD:275368 7/19 (37%)
zf-H2C2_2 418..443 CDD:290200 10/24 (42%)
C2H2 Zn finger 434..454 CDD:275368 8/19 (42%)
zf-H2C2_2 446..471 CDD:290200 9/24 (38%)
C2H2 Zn finger 462..482 CDD:275368 7/19 (37%)
zf-H2C2_2 474..499 CDD:290200 6/25 (24%)
C2H2 Zn finger 490..510 CDD:275368 5/19 (26%)
zf-H2C2_2 502..527 CDD:290200 9/25 (36%)
C2H2 Zn finger 518..538 CDD:275368 8/19 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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