DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sry-beta and CG6791

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_650090.1	Gene:	CG6791 / 41391	FlyBaseID:	FBgn0037918	Length:	1243	Species:	Drosophila melanogaster

Alignment Length:	371	Identity:	86/371 - (23%)
Similarity:	133/371 - (35%)	Gaps:	110/371 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 EKII----------NQRLELLPNS--AACRDCLEYLFNYDRLVRNLSQVQRQIADALLGC-RQVE 94
            :|||          ..|:..||..  |.||.|.:...:...||::|:...|      :|. |::.
  Fly   561 DKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATHHR------VGWPRKLS 619

  Fly    95 GKAETK-QQAAKRARVQV-----PAFKIVQATALKEPERQPGEED-ECEEFMKEEMLDEEFQFSE 152
            |..... ...||:.|.|:     ..::|:.   |.:.::...||| :..|.|:.|  ::|:..:.
  Fly   620 GGCPAPILTPAKQPRKQIVTVANETYEIIY---LDDVDQGGMEEDNDFGEQMQAE--EDEYPIAP 679

  Fly   153 PDDSMPSSEEEFFTETTE-----IPCHICGEMFSSQEVLERHIKADTCQKS-------------- 198
            |..|.|...:    .||:     ..|..||.:|::|..:..||....|:|:
  Fly   680 PPPSPPPPPQ----PTTQGNHQRYKCVHCGTLFATQAAVRVHISEKRCRKTVVRRRRQPVMSSAD 740

  Fly   199 ------EQ---ATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHM-EVH-- 251
                  ||   ..|..||.               |.||:.|.|             ||: |||
  Fly   741 PSVPTVEQNYIFLCPSCGF---------------EYKTQFEWR-------------RHINEVHNF 777

  Fly   252 ----------WDKKKYQCDKCGERFSLSWL--MYNHLMRHDAEENALICEVCHQQFKTKRTYKHH 304
                      .||.:|||.:|.:....|.|  :.:|..||......|.|.:|...:..|.....|
  Fly   778 DKRQYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAH 842

  Fly   305 LRTHQT--DRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKPESAEA 348
            ||...:  ||.........|..:.:|  |.:.|.:..:..|..|.|
  Fly   843 LRARHSIFDRETPTMITKPKQVLGRY--KDNSRENPKLPSPPPAPA 886

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	3/19 (16%)
		C2H2 Zn finger	231..251	CDD:275368	4/20 (20%)
		C2H2 Zn finger	259..308	CDD:275368	14/50 (28%)
		C2H2 Zn finger	288..303	CDD:275370	3/14 (21%)
		zf-C2H2	315..337	CDD:278523	4/21 (19%)
		C2H2 Zn finger	317..337	CDD:275368	4/19 (21%)
CG6791	NP_650090.1	C2H2 Zn finger	167..188	CDD:275368
		C2H2 Zn finger	208..230	CDD:275368
		C2H2 Zn finger	235..256	CDD:275368
		C2H2 Zn finger	516..532	CDD:275368
		C2H2 Zn finger	557..580	CDD:275368	4/18 (22%)
		C2H2 Zn finger	589..609	CDD:275368	6/19 (32%)
		COG5236	<939..>1096	CDD:227561
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100