DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and CG10654

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster

Alignment Length:	315	Identity:	67/315 - (21%)
Similarity:	118/315 - (37%)	Gaps:	101/315 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 RDCLEYLFNYDRLVRNLSQVQRQIADALLGCRQVEG--------KAETKQQAAKRARVQVPAFKI 116
            |.|.|.|.|:::|::::.          :||.::|.        .:|:.:.....|:...|....
  Fly   103 RMCAESLRNFEKLLQDID----------IGCHKLEDHTWHDLDTPSESNESTNPEAQSHAPCIAA 157

  Fly   117 VQATALKEPERQPGEEDECEEFMKEEMLDEEFQFSEPDDSMP------------SSEEEFFTETT 169
            .|                           |...|..|...:|            |.|||.:.
  Fly   158 TQ---------------------------EIVSFIWPQVCLPLAVILSRITLGASLEEEVYV--- 192

  Fly   170 EIPCHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEG-KTELECRY 233
                           :.:...|.|..|:....:..:.|.:.:            .| :..||||.
  Fly   193 ---------------IEDESAKQDLGQEKLSISSKLLGARKR------------RGVRHTLECRI 230

  Fly   234 CDKKFSHKRNVLR-HMEVHWDKKKYQCDKCGERFSLSWLMYNHL--MRHDAEENALI--CEVCHQ 293
            |.:.| :|.::|. ||:.|...:.|.|..|.:.::.:.|:.:||  |.::|:...:|  |..|::
  Fly   231 CHRGF-YKPSLLEAHMQQHEGLRPYTCVHCAKSYARANLLESHLRQMHNNADAARIIYACPSCNK 294

  Fly   294 QFKTKRTYKHHLRT-----HQTDRP--RYPCPDCEKSFVDKYTLKVHKRVHQPVE 341
            .:...|:.|:|:|.     |:::.|  |:.|.:|.|.|..|..|..||.||..||
  Fly   295 VYTANRSLKYHMRRTHERYHESESPDARHICEECGKCFARKAHLTRHKMVHGSVE 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	1/19 (5%)
		C2H2 Zn finger	231..251	CDD:275368	8/20 (40%)
		C2H2 Zn finger	259..308	CDD:275368	14/57 (25%)
		C2H2 Zn finger	288..303	CDD:275370	3/14 (21%)
		zf-C2H2	315..337	CDD:278523	8/21 (38%)
		C2H2 Zn finger	317..337	CDD:275368	8/19 (42%)
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071	5/11 (45%)
		C2H2 Zn finger	228..248	CDD:275368	8/20 (40%)
		C2H2 Zn finger	256..313	CDD:275368	14/56 (25%)
		C2H2 Zn finger	289..314	CDD:275368	6/24 (25%)
		zf-C2H2	323..345	CDD:278523	8/21 (38%)
		C2H2 Zn finger	325..345	CDD:275368	8/19 (42%)
		C2H2 Zn finger	355..376	CDD:275368
		C2H2 Zn finger	385..405	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100