DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and Zfp157

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	XP_038945496.1	Gene:	Zfp157 / 360775	RGDID:	1359435	Length:	569	Species:	Rattus norvegicus

Alignment Length:	306	Identity:	83/306 - (27%)
Similarity:	131/306 - (42%)	Gaps:	41/306 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 CLE----YLFNYDRLVRNLSQVQRQIADALLGCRQVEGKAETKQQAAKRARVQVPAFKIVQATAL 122
            |||    :::....:.||||..:...|:..:   |:|....||....|      |..|:|.....
  Rat    88 CLENPESHMWPVGSISRNLSNKEMIEAEMKV---QLELYRGTKPCECK------PCMKMVSLPLQ 143

  Fly   123 KEPER------QPGEEDECEE-FMKEEMLDEEFQFSEPDDSMPSSEEEFFTETTEIPCHICGEMF 180
            :..:.      :|.|..||:: |..:..|.:.        ..|.:..:.:      .|..|.:.|
  Rat   144 RNEQHAYYARVKPYEWKECQKAFCYKSALTQH--------QRPRTRLKIY------QCTECRKAF 194

  Fly   181 SSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVL 245
            .|:..|..|.:..|.:|..:  |:.||........|.:|...|.|:...||:.|.|.|.:|..:.
  Rat   195 PSKSELTVHHRIHTGEKPHE--CDECGKAFYRKSTLTVHQKTHRGEKPYECKECCKAFYYKSTLT 257

  Fly   246 RHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLRTHQT 310
            .|..:|..:|.|.|.:||:.|.....:..|...|..|: ...||.|.:.|.:|.....|.|||..
  Rat   258 EHQRIHTGEKPYVCKECGKAFFYKSNLTRHHRTHTGEK-PYECEECRKGFSSKSELTSHHRTHTG 321

  Fly   311 DRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKPESAEAKEATVTFF 356
            ::| |.|.:|.|:|..|.||:||:::|.. |||  .|.||...:|:
  Rat   322 EKP-YQCEECGKAFYCKSTLRVHQKIHTG-EKP--YECKECQKSFY 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	5/19 (26%)
		C2H2 Zn finger	231..251	CDD:275368	6/19 (32%)
		C2H2 Zn finger	259..308	CDD:275368	14/48 (29%)
		C2H2 Zn finger	288..303	CDD:275370	5/14 (36%)
		zf-C2H2	315..337	CDD:278523	10/21 (48%)
		C2H2 Zn finger	317..337	CDD:275368	9/19 (47%)
Zfp157	XP_038945496.1	KRAB	5..65	CDD:214630
		C2H2 Zn finger	160..179	CDD:275368	4/26 (15%)
		COG5048	183..529	CDD:227381	60/194 (31%)
		C2H2 Zn finger	187..207	CDD:275368	6/19 (32%)
		C2H2 Zn finger	215..235	CDD:275368	5/19 (26%)
		C2H2 Zn finger	243..263	CDD:275368	6/19 (32%)
		C2H2 Zn finger	271..291	CDD:275368	5/19 (26%)
		C2H2 Zn finger	299..319	CDD:275368	7/19 (37%)
		C2H2 Zn finger	327..347	CDD:275368	9/19 (47%)
		C2H2 Zn finger	355..375	CDD:275368	3/9 (33%)
		C2H2 Zn finger	383..403	CDD:275368
		C2H2 Zn finger	411..431	CDD:275368
		C2H2 Zn finger	439..459	CDD:275368
		C2H2 Zn finger	467..487	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000