DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sry-beta and ZBTB41

DIOPT Version :9

Sequence 1:NP_001303451.1 Gene:Sry-beta / 43570 FlyBaseID:FBgn0003511 Length:356 Species:Drosophila melanogaster
Sequence 2:NP_919290.2 Gene:ZBTB41 / 360023 HGNCID:24819 Length:909 Species:Homo sapiens


Alignment Length:317 Identity:78/317 - (24%)
Similarity:129/317 - (40%) Gaps:65/317 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    90 CRQVEGKAETKQQAAKRARVQVPAFKIVQATALKEPERQPGEEDECEE-FMKEEMLDEEFQFSEP 153
            |.::....:|..:..||...:    ...:..::|:.:.:..:.|.|:: |.:...|:|.......
Human   427 CNKLHASKKTLAKHVKRFHPE----NAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQ 487

  Fly   154 DDSMPSS--EEEFFTETTEI-----------PCHICGEMFSSQEVLERHIKADTCQKSEQATCNV 205
            |.....:  ||.|.:....:           ||.|||..|:....|:|||:. |.....:.||.:
Human   488 DKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIEC-THGGKRKWTCFI 551

  Fly   206 CGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSW 270
            ||..|::...|..|:.:|.|:....|..|.:.|.|..:...|:.||.|.|:|:||:||:.|    
Human   552 CGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTF---- 612

  Fly   271 LMYNHLMR----------HDAEENALI------------------------------CEVCHQQF 295
            :.::||.:          |..||....                              |:||.:.|
Human   613 IRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCDVCKKIF 677

  Fly   296 KTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKPESAEAKEAT 352
            |.|.:.:.|.|||..::| |.|..|.:||..|.||..|..:|... :|.:.:...||
Human   678 KGKSSLEMHFRTHSGEKP-YKCQICNQSFRIKKTLTKHLVIHSDA-RPFNCQHCNAT 732

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sry-betaNP_001303451.1 C2H2 Zn finger 203..223 CDD:275368 6/19 (32%)
C2H2 Zn finger 231..251 CDD:275368 5/19 (26%)
C2H2 Zn finger 259..308 CDD:275368 18/88 (20%)
C2H2 Zn finger 288..303 CDD:275370 6/14 (43%)
zf-C2H2 315..337 CDD:278523 9/21 (43%)
C2H2 Zn finger 317..337 CDD:275368 8/19 (42%)
ZBTB41NP_919290.2 BTB_POZ_ZBTB41 66..179 CDD:349535
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 252..344
C2H2 Zn finger 363..383 CDD:275368
C2H2 Zn finger 391..411 CDD:275368
C2H2 Zn finger 424..442 CDD:275368 2/14 (14%)
C2H2 Zn finger 465..485 CDD:275368 5/19 (26%)
C2H2 Zn finger 493..510 CDD:275368 3/16 (19%)
C2H2 Zn finger 520..541 CDD:275368 9/21 (43%)
C2H2 Zn finger 549..569 CDD:275368 6/19 (32%)
C2H2 Zn finger 577..597 CDD:275368 5/19 (26%)
zf-C2H2 603..625 CDD:395048 8/25 (32%)
C2H2 Zn finger 605..625 CDD:275368 7/23 (30%)
C2H2 Zn finger 633..651 CDD:275368 2/17 (12%)
C2H2 Zn finger 670..687 CDD:275368 6/16 (38%)
C2H2 Zn finger 698..718 CDD:275368 8/19 (42%)
C2H2 Zn finger 726..743 CDD:275368 2/7 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S4053
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.950

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