DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and az2

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_610289.2	Gene:	az2 / 35682	FlyBaseID:	FBgn0025185	Length:	593	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	56/249 - (22%)
Similarity:	92/249 - (36%)	Gaps:	46/249 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 VQATALKEPERQPGEEDECEEFMKEEMLDEEFQFSEPDDSMPSSEEEFFTETTEIPCHICGEMFS 181
            ||...|...|:|..|  .|..||..:...:                       ::.|.:|...||
  Fly   346 VQCVGLSLAEKQYIE--RCNSFMPTKSFRQ-----------------------KLKCEVCEHSFS 385

  Fly   182 SQEVLERHIKADTCQKSEQA---TCNVCGLKVKDDEVLDLHMNLHEGKTELE----CRYCDKKFS 239
            :...|:.|...|  .|....   .|.:|.|...    ...|:..|..:..::    |..|.:.|:
  Fly   386 TDHALQAHQFRD--HKMGDGGWFRCTLCELNFD----RKCHLQQHSQRVHMDKSFVCEICSRSFA 444

  Fly   240 HKRNVLRHMEVHWDK---KKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKRTY 301
            ....:..|...|.:|   |.:.|:.||:.|.....|..|:.....:..|..|::|.:.|.|||..
  Fly   445 FGNQLAIHKRTHDEKHVAKPFVCEFCGKCFKQKIQMTTHVTAVHTKIRAFKCDMCPKDFLTKRDL 509

  Fly   302 KHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKPESAEAKEATVTF 355
            |.|::.|...|.:. |..|:|:|.:...|..|:.:|    |.::.:....|..|
  Fly   510 KDHVKAHLNIRDKV-CEVCQKAFTNANALVKHRHIH----KEKTLQCSLCTTRF 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	4/19 (21%)
		C2H2 Zn finger	231..251	CDD:275368	4/19 (21%)
		C2H2 Zn finger	259..308	CDD:275368	15/48 (31%)
		C2H2 Zn finger	288..303	CDD:275370	6/14 (43%)
		zf-C2H2	315..337	CDD:278523	6/21 (29%)
		C2H2 Zn finger	317..337	CDD:275368	6/19 (32%)
az2	NP_610289.2	MADF_DNA_bdg	157..242	CDD:287510
		GT1	276..>341	CDD:304916
		C2H2 Zn finger	377..398	CDD:275368	7/22 (32%)
		C2H2 Zn finger	408..429	CDD:275368	5/24 (21%)
		C2H2 Zn finger	436..456	CDD:275368	4/19 (21%)
		C2H2 Zn finger	467..488	CDD:275368	6/20 (30%)
		C2H2 Zn finger	496..516	CDD:275368	8/19 (42%)
		C2H2 Zn finger	524..544	CDD:275368	6/19 (32%)
		C2H2 Zn finger	551..572	CDD:275368	2/8 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100