DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sry-beta and CG1529

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	357	Identity:	84/357 - (23%)
Similarity:	139/357 - (38%)	Gaps:	63/357 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 TFKPIKDILKYFEKIINQRLELLPN---SAACRDCLEYLFNYDRLVRNLSQVQRQIADALLGCRQ 92
            |..|...::...:|:::..:...|:   :..|..|...:..:|    .|.||.|:.:..|:|.:.
  Fly    24 THCPDPRLIAILQKLLDIDILKQPHGFPTEICNLCHNAVVYFD----ELRQVARESSQKLIGWQP 84

  Fly    93 V---------------------EGKAETKQQAAKRARVQVPAFKIVQATALKEPERQPGEEDECE 136
            |                     |.:.|.:::..|:|..|       |....|:.|.|....|:.|
  Fly    85 VDIAVDRVKEEPPDEGLKENHEENEHELEEEHEKQADGQ-------QVDLSKKQEDQKKILDDRE 142

  Fly   137 EFMKEEMLDEEFQFSEPDDSMPSSEEEFFTET-----TEIPCHICGEMFSSQEVLERHIKADTCQ 196
                    |||:    ||: ..:|:::....|     ..:.|..||:.......||.||::....
  Fly   143 --------DEEY----PDE-YENSQQQLSQGTGSKRRAGLACDQCGKQVYKLPYLEAHIRSVHQG 194

  Fly   197 KSEQATCNVCGLKVKDDEVLDLHM-NLHEGKTELE-------CRYCDKKFSHKRNVLRHMEVHWD 253
            .|:...|..|.......|.|..|| |.|....:|:       |..|::::|.|..:..|::.|..
  Fly   195 YSKPFLCRSCDKSFTRYEQLRSHMRNAHPQLEQLQQELRDLICELCNRQYSTKNALGEHLKRHAQ 259

  Fly   254 KKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCP 318
            :|::.|:.||........:..||..|:.......||.|.|.|:.|.....|:|.....:.|:.|.
  Fly   260 RKEHVCEHCGVAKVTRTELLTHLRTHNPTWERFKCEQCPQLFRHKSAISRHVRVVHEGQRRFQCG 324

  Fly   319 DCEKSFVDKYTLKVHKRVHQPVEKPESAEAKE 350
            .|||.|....:...|:|:|  .|...|.||.|
  Fly   325 HCEKKFGTHASQVRHERLH--TESTGSGEAAE 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	7/20 (35%)
		C2H2 Zn finger	231..251	CDD:275368	5/19 (26%)
		C2H2 Zn finger	259..308	CDD:275368	14/48 (29%)
		C2H2 Zn finger	288..303	CDD:275370	6/14 (43%)
		zf-C2H2	315..337	CDD:278523	7/21 (33%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071	11/58 (19%)
		C2H2 Zn finger	171..192	CDD:275368	7/20 (35%)
		zf-C2H2_2	201..>257	CDD:289522	14/55 (25%)
		C2H2 Zn finger	201..222	CDD:275368	7/20 (35%)
		C2H2 Zn finger	237..257	CDD:275368	5/19 (26%)
		C2H2 Zn finger	265..285	CDD:275368	5/19 (26%)
		zf-C2H2_8	268..349	CDD:292531	23/82 (28%)
		C2H2 Zn finger	294..315	CDD:275368	8/20 (40%)
		C2H2 Zn finger	323..343	CDD:275368	7/19 (37%)
		C2H2 Zn finger	360..380	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100