DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and Zfp182

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	XP_036017871.1	Gene:	Zfp182 / 319535	MGIID:	2442220	Length:	682	Species:	Mus musculus

Alignment Length:	344	Identity:	91/344 - (26%)
Similarity:	143/344 - (41%)	Gaps:	56/344 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 FQLIEGCIVPGTFKPIKDILKY--FEKIINQRLELLPNSAA----CRDCLEYLFNYDRLVRNLSQ 78
            |.|..|.:|     |::...|:  |...:...|.||..|:.    ...|.::.|:.:  ..|.:.
Mouse   200 FHLSTGLLV-----PMQRSHKFESFGNTMVDNLNLLTGSSTENKHDTGCAKFFFHTE--YENPNF 257

  Fly    79 VQRQIADALLGCRQVEGKAETKQQAAKRARVQVPAFKIVQATALKEPERQPGEEDECEE-FMKEE 142
            :.:.     .|.::.|.....|:..:...|:             |..|| |.|...|:: |.|:.
Mouse   258 IVKP-----CGYKEYEKTLRQKKGLSLHQRI-------------KNGER-PFECTACQKTFSKKS 303

  Fly   143 MLDEEFQFSEPDDSMPSSEEEFFTETTEIP--CHICGEMFSSQEVLERHIKADTCQKSEQATCNV 205
            .|...::                |.|.|.|  |..||:.||.:..|..|::..|.::  ...|..
Mouse   304 HLIVHWR----------------THTGEKPFECSECGKAFSQKSQLIIHLRTHTGER--PFACPE 350

  Fly   206 CGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSW 270
            ||...::...:.:|...|.|:...||..|.|.|:.|.|::.|.:.|..:|.|:|.||||.|....
Mouse   351 CGKAFREKSTVIIHYRTHTGEKPYECNQCGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKL 415

  Fly   271 LMYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKR 335
            .:..|...|..:: ...|..|.:.|..|.|...|.|||..::| :.|.:|.|||.:|.||.||:|
Mouse   416 DLIIHHSTHTGKK-PHECSECKKTFSDKSTLVIHQRTHTGEKP-HKCTECGKSFNEKSTLIVHQR 478

  Fly   336 VHQPVEKPESAEAKEATVT 354
            :|.. |||...:....|.|
Mouse   479 IHTG-EKPYECDVCGKTFT 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	4/19 (21%)
		C2H2 Zn finger	231..251	CDD:275368	7/19 (37%)
		C2H2 Zn finger	259..308	CDD:275368	15/48 (31%)
		C2H2 Zn finger	288..303	CDD:275370	5/14 (36%)
		zf-C2H2	315..337	CDD:278523	11/21 (52%)
		C2H2 Zn finger	317..337	CDD:275368	11/19 (58%)
Zfp182	XP_036017871.1	KRAB	63..139	CDD:214630
		COG5048	288..677	CDD:227381	71/231 (31%)
		C2H2 Zn finger	292..312	CDD:275368	4/35 (11%)
		C2H2 Zn finger	320..340	CDD:275368	7/19 (37%)
		C2H2 Zn finger	348..368	CDD:275368	4/19 (21%)
		C2H2 Zn finger	376..396	CDD:275368	7/19 (37%)
		C2H2 Zn finger	404..424	CDD:275368	7/19 (37%)
		C2H2 Zn finger	432..452	CDD:275368	7/19 (37%)
		C2H2 Zn finger	460..480	CDD:275368	11/19 (58%)
		C2H2 Zn finger	488..508	CDD:275368	2/9 (22%)
		C2H2 Zn finger	516..536	CDD:275368
		C2H2 Zn finger	544..564	CDD:275368
		C2H2 Zn finger	572..592	CDD:275368
		C2H2 Zn finger	600..620	CDD:275368
		C2H2 Zn finger	628..648	CDD:275368
		C2H2 Zn finger	656..676	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000