DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and CG2120

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_572446.2	Gene:	CG2120 / 31737	FlyBaseID:	FBgn0030005	Length:	315	Species:	Drosophila melanogaster

Alignment Length:	259	Identity:	61/259 - (23%)
Similarity:	92/259 - (35%)	Gaps:	62/259 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 TALKEPERQP--------GEEDECEEFMKEEMLDEEFQFSEPDDSMPSSEEEF------FTETTE 170
            |.:.:|:|.|        |::..|      ::.|..|            .|.:      .|.|.|
  Fly    78 TDMCKPKRTPTTKRHRTTGKDHTC------DICDRRF------------SEAYNLRIHKMTHTDE 124

  Fly   171 IP--CHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRY 233
            .|  |..||:.|.....|..|....|.::..:  |::||...:....|.:|..||.|:....|..
  Fly   125 KPHVCVECGKGFRQLNKLRIHAVTHTAERPHK--CDICGKGFRYANYLTVHRRLHTGEKPYPCLA 187

  Fly   234 CDKKFS----HKRNV---LRH-MEVHWDKK--------------KYQCDKCGERFSLSWLMYNHL 276
            .|...|    |.|.:   ||| .:...|.:              .:.|..|....:....:..||
  Fly   188 TDCHLSFHSIHARRIHTKLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHL 252

  Fly   277 MRHDAEENALIC--EVCHQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQ 338
            .|| ..:....|  ..|.::|.:....|||...|...|| :.||.|...|:.|...|.|.:||:
  Fly   253 KRH-YNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRP-FACPLCPARFLRKSNHKQHLKVHE 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	5/19 (26%)
		C2H2 Zn finger	231..251	CDD:275368	8/27 (30%)
		C2H2 Zn finger	259..308	CDD:275368	12/50 (24%)
		C2H2 Zn finger	288..303	CDD:275370	3/16 (19%)
		zf-C2H2	315..337	CDD:278523	7/21 (33%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	4/37 (11%)
		zf-H2C2_2	113..138	CDD:290200	8/24 (33%)
		C2H2 Zn finger	129..149	CDD:275368	6/19 (32%)
		zf-H2C2_2	142..166	CDD:290200	6/25 (24%)
		COG5048	151..>264	CDD:227381	23/115 (20%)
		C2H2 Zn finger	157..177	CDD:275368	5/19 (26%)
		C2H2 Zn finger	185..206	CDD:275368	5/20 (25%)
		C2H2 Zn finger	235..255	CDD:275368	4/19 (21%)
		C2H2 Zn finger	263..285	CDD:275368	6/21 (29%)
		C2H2 Zn finger	293..313	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446556
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030