DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and CG11398

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_001259122.2	Gene:	CG11398 / 31070	FlyBaseID:	FBgn0040366	Length:	329	Species:	Drosophila melanogaster

Alignment Length:	200	Identity:	52/200 - (26%)
Similarity:	77/200 - (38%)	Gaps:	13/200 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 EEFQFSEPDDSMPSSEEEFFTETTEIPCHICGEMFSSQEVLERHIKADTCQKSEQA-----TCNV 205
            ||.||.|.::.....:    ..:....|..|..:|.::|.|..|......|..:|.     .|:.
  Fly    29 EELQFEELNERSQHQQ----GGSPSFVCRRCPALFLTREELAAHRPTHRYQGGQQTPASEHACDA 89

  Fly   206 CGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHME-VHWDKKKYQCDK--CGERFS 267
            ||...:....|..|||.|.......|..|..:|..:.|...|:: ||.....:.|.:  |.:||.
  Fly    90 CGRVFQKHNALVDHMNAHNDVRNYPCPECPARFVQRSNRECHLKNVHRKVYLHSCPEPGCKKRFQ 154

  Fly   268 LSWLMYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKV 332
            .......|:......|..|:|:.|..:|.....|:.||.:|.:.: .|.||.|.|.|.......|
  Fly   155 QRRECDQHVKTVHQNERNLVCDTCSARFSHPVNYRKHLASHGSAK-SYGCPICGKLFGRPENRDV 218

  Fly   333 HKRVH 337
            |..||
  Fly   219 HLFVH 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	7/19 (37%)
		C2H2 Zn finger	231..251	CDD:275368	5/20 (25%)
		C2H2 Zn finger	259..308	CDD:275368	13/50 (26%)
		C2H2 Zn finger	288..303	CDD:275370	4/14 (29%)
		zf-C2H2	315..337	CDD:278523	8/21 (38%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
CG11398	NP_001259122.2	C2H2 Zn finger	52..72	CDD:275368	6/19 (32%)
		C2H2 Zn finger	87..107	CDD:275368	7/19 (37%)
		C2H2 Zn finger	115..136	CDD:275368	5/20 (25%)
		C2H2 Zn finger	144..165	CDD:275368	5/20 (25%)
		C2H2 Zn finger	175..195	CDD:275368	6/19 (32%)
		C2H2 Zn finger	203..223	CDD:275368	7/19 (37%)
		C2H2 Zn finger	231..247	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449832
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030