DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and Opbp

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_724479.1	Gene:	Opbp / 246618	FlyBaseID:	FBgn0050443	Length:	562	Species:	Drosophila melanogaster

Alignment Length:	356	Identity:	87/356 - (24%)
Similarity:	149/356 - (41%)	Gaps:	74/356 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VGVFQLIEGCIVPGTFKPIKD------ILKYFEKIINQRLELLPNSAACRDCLEYLFNYDRLVRN 75
            |.:::|:|.  ||...|..||      ..:||                |.||       ..:..|
  Fly    89 VPLWELVEE--VPANVKAEKDQNEPSNSDRYF----------------CYDC-------HSIFEN 128

  Fly    76 LSQVQRQIADALLGCRQVEGKAETKQQAAKRARVQVPAFKIVQATALKEPERQPGEEDEC----- 135
            .::.:..|      |.:.|....::|....:|.|:   .|:...:|...| |.......|
  Fly   129 RNKAEEHI------CPRAESGGSSQQDGDAKAPVR---RKLASVSARTGP-RDASSVISCGICNT 183

  Fly   136 ----EEFMKEEM-LDEEFQFSEPDDSMPSSEEEFFTETTEIPCHICGEMFSSQEVLERHIKADTC 195
                |:|:|..| :.|........|::|....:.::|..:..|.||.:.| .:.:|..| |....
  Fly   184 VFSSEKFLKFHMRIHENRAPKSIQDALPIGAHQQYSELDQFYCEICNKSF-DETLLTVH-KQMHQ 246

  Fly   196 QKSEQATCNVCGLKVKDDEVLDLHMNLHE------------GKTELE-------CRYCDKKFSHK 241
            |:|.:..|::|..|.:::....:|..:||            .:|.|:       |:||::.|:..
  Fly   247 QESSEIMCSICNRKFENEVTYQMHQKIHEKPRDSESSRKLAQRTSLDKEKPGFPCQYCERVFTRP 311

  Fly   242 RNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLR 306
            ...::|..||..:|.|.|:.||:.|.:|:.:..||..| ......:|.||:::||:.:.|.||||
  Fly   312 FEKVKHERVHTGEKPYACEVCGKTFRVSYSLTLHLRTH-TNIRPYVCTVCNKRFKSHQVYSHHLR 375

  Fly   307 THQTDRPRYPCPDCEKSFVDKYTLKVHKRVH 337
            .|.::| ::.|..|.|:|.....|..||..|
  Fly   376 IHSSER-QFSCDACPKTFRTSVQLYAHKNTH 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	4/19 (21%)
		C2H2 Zn finger	231..251	CDD:275368	5/19 (26%)
		C2H2 Zn finger	259..308	CDD:275368	18/48 (38%)
		C2H2 Zn finger	288..303	CDD:275370	6/14 (43%)
		zf-C2H2	315..337	CDD:278523	7/21 (33%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
Opbp	NP_724479.1	C2H2 Zn finger	254..274	CDD:275368	4/19 (21%)
		C2H2 Zn finger	301..321	CDD:275368	5/19 (26%)
		zf-H2C2_2	316..336	CDD:290200	8/19 (42%)
		C2H2 Zn finger	329..349	CDD:275368	7/19 (37%)
		zf-H2C2_2	341..366	CDD:290200	7/25 (28%)
		C2H2 Zn finger	357..377	CDD:275368	10/19 (53%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		C2H2 Zn finger	411..431	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100