DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and let-391

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_491744.3	Gene:	let-391 / 182953	WormBaseID:	WBGene00006492	Length:	453	Species:	Caenorhabditis elegans

Alignment Length:	291	Identity:	64/291 - (21%)
Similarity:	106/291 - (36%)	Gaps:	54/291 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PIKDILKYFEKII--NQRLELLPNSAACR----DCLEYLFNYDRLVRNLSQVQRQIADALLGCRQ 92
            |.:..||..:||:  :..:::|.|||...    ..::.:|..|....:.|..|.|.::.......
Worm   145 PARPYLKPVKKIVCPSMDMDILSNSALANYISPPTIDSIFQSDPSTSSSSPSQFQSSNQTTKQSI 209

  Fly    93 VEGKAETKQQAAKRARVQVPAFKIVQATALKEPERQPGEEDECEEFMKEEMLDEEFQFSEPDDSM 157
            ...:.|.::.|...||:. .....|.|..|..                   :|||....||:.:.
Worm   210 YPSEKEMEKAAISNARID-DVINTVLARVLAP-------------------IDEEIPIEEPEKAP 254

  Fly   158 PSSEEEFFTETTEIPCHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHM-N 221
            ...........|...|:|||.|......:..||:..|.:|..:  |..|||.:.....|.:|: .
Worm   255 QKRAYISNRRATLAQCNICGLMLKHPSKIADHIRTHTGEKPFE--CGECGLSLSKASSLKVHIRR 317

  Fly   222 LHEGKTELECRY-CDKKFSHKRNVLRH-MEVHWDKKKYQCDKCGERFSLSWLMYNHLMRH----- 279
            :|.|:...||.: |...|........| |.||...|:|.|...|.....:..:|  ||||
Worm   318 MHTGERPFECTWRCGLSFVTDSVRKEHEMTVHTGIKRYTCVVKGCNAVFARRVY--LMRHRKNAH 380

  Fly   280 ----------------DAEENALICEVCHQQ 294
                            :::::.::.|..|:|
Worm   381 PELFTPIFDHVQVNHEESQDSVIVYEDDHEQ 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	6/20 (30%)
		C2H2 Zn finger	231..251	CDD:275368	5/21 (24%)
		C2H2 Zn finger	259..308	CDD:275368	10/57 (18%)
		C2H2 Zn finger	288..303	CDD:275370	3/7 (43%)
		zf-C2H2	315..337	CDD:278523
		C2H2 Zn finger	317..337	CDD:275368
let-391	NP_491744.3	C2H2 Zn finger	59..79	CDD:275368
		zf-H2C2_2	73..96	CDD:290200
		C2H2 Zn finger	87..108	CDD:275368
		C2H2 Zn finger	116..137	CDD:275368
		C2H2 Zn finger	270..290	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..304	CDD:290200	7/19 (37%)
		C2H2 Zn finger	298..319	CDD:275368	6/20 (30%)
		C2H2 Zn finger	327..347	CDD:275368	4/19 (21%)
		C2H2 Zn finger	357..377	CDD:275368	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100