DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and unc-98

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_509284.2	Gene:	unc-98 / 181020	WormBaseID:	WBGene00006827	Length:	310	Species:	Caenorhabditis elegans

Alignment Length:	279	Identity:	54/279 - (19%)
Similarity:	87/279 - (31%)	Gaps:	92/279 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 EEDECEEFM-----------KEEMLDEEFQFSEPDDSMPSSEEEFFTETTEIPCHICGEMFSSQE 184
            |.|:.||.|           ..||:.....|....:|..:..:|...|..::..          .
Worm    12 ERDDFEELMNACDLAKMSVKNNEMVHGLETFGINGESSENGNKEKPKEIMKVVA----------P 66

  Fly   185 VLERHIKADTCQK-----------SEQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYCDKKF 238
            .:|.::.:.:.|.           |:|......|..|:.|:         .|....:||:|...|
Worm    67 TVEAYVGSSSAQTPTKSSGGALDGSDQQEVRQDGTSVQKDD---------NGFVFYKCRFCGLTF 122

  Fly   239 SHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQF--KTKRTY 301
            :....:..|..:|...:.|.|.|||:.|..:..:..|..:| :|.:...|| |.:.|  .|:..|
Worm   123 NFMNTLRAHERIHDVSQPYVCGKCGDSFEFACQLEYHAAQH-SEIDGYKCE-CGRTFFSYTEMLY 185

  Fly   302 ----------------------------------------------KHHLRTHQTDRPR-YPCPD 319
                                                          ||.||.:...|.: |.|..
Worm   186 HKHTDDPLELIGAPETTTIKVSKKRVLPVSEQDLPQPAFVTEGYEPKHPLRVYNDVRSKPYICEY 250

  Fly   320 CEKSFVDKYTLKVHKRVHQ 338
            |.||:.|...|..|...|:
Worm   251 CSKSYSDSRGLAYHMYSHR 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	3/19 (16%)
		C2H2 Zn finger	231..251	CDD:275368	5/19 (26%)
		C2H2 Zn finger	259..308	CDD:275368	18/96 (19%)
		C2H2 Zn finger	288..303	CDD:275370	6/62 (10%)
		zf-C2H2	315..337	CDD:278523	8/21 (38%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
unc-98	NP_509284.2	C2H2 Zn finger	115..135	CDD:275368	5/19 (26%)
		C2H2 Zn finger	143..163	CDD:275368	6/19 (32%)
		SFP1	<169..268	CDD:227516	19/99 (19%)
		C2H2 Zn finger	171..189	CDD:275368	6/18 (33%)
		C2H2 Zn finger	248..268	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100