DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sry-beta and ZNF679

DIOPT Version :9

Sequence 1:NP_001303451.1 Gene:Sry-beta / 43570 FlyBaseID:FBgn0003511 Length:356 Species:Drosophila melanogaster
Sequence 2:NP_699194.2 Gene:ZNF679 / 168417 HGNCID:28650 Length:411 Species:Homo sapiens


Alignment Length:312 Identity:76/312 - (24%)
Similarity:124/312 - (39%) Gaps:33/312 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    53 LPNSAACRDCLEYLF-------NYDRL----VRNLSQVQRQIADALLGCRQVEGKAETKQQAAKR 106
            ||.....:|.|:.:.       .:|.|    .:::.:.:.|..    ||.:|.....|.|....:
Human    97 LPPELGIKDSLQKVIPRRYGKSGHDNLQVKTCKSMGECEVQKG----GCNEVNQCLSTTQNKIFQ 157

  Fly   107 ARVQVPAF-KIVQATALKEPERQPGEED-ECEEFMKEEMLDEEFQFSEPDDSMPSSEEEFFTETT 169
            ....|..| |.  :.:.:...|..|::. :|:::.|...:..:..          ..:...|...
Human   158 THKCVKVFGKF--SNSNRHKTRHTGKKHFKCKKYGKSFCMVSQLH----------QHQIIHTREN 210

  Fly   170 EIPCHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYC 234
            ...|..||:.|:....|.:|.:..|.:|..:  |..||........|..|..:|.|:....|..|
Human   211 SYQCEECGKPFNCSSTLSKHKRIHTGEKPYR--CEECGKAFTWSSTLTKHRRIHTGEKPYTCEEC 273

  Fly   235 DKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKR 299
            .:.||....:..|..:|..:|.|.|::||:.||||..:..|...|..|: ...||.|.:.|....
Human   274 GQAFSRSSTLANHKRIHTGEKPYTCEECGKAFSLSSSLTYHKRIHTGEK-PYTCEECGKAFNCSS 337

  Fly   300 TYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKPESAEAKEA 351
            |.|.|...|..::| |.|.:|.|:|....||..|||:|...|..:..|..:|
Human   338 TLKKHKIIHTGEKP-YKCKECGKAFAFSSTLNTHKRIHTGEEPYKCEECDKA 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sry-betaNP_001303451.1 C2H2 Zn finger 203..223 CDD:275368 5/19 (26%)
C2H2 Zn finger 231..251 CDD:275368 5/19 (26%)
C2H2 Zn finger 259..308 CDD:275368 17/48 (35%)
C2H2 Zn finger 288..303 CDD:275370 5/14 (36%)
zf-C2H2 315..337 CDD:278523 10/21 (48%)
C2H2 Zn finger 317..337 CDD:275368 9/19 (47%)
ZNF679NP_699194.2 KRAB 16..76 CDD:214630
KRAB 16..55 CDD:279668
C2H2 Zn finger 159..178 CDD:275368 3/20 (15%)
C2H2 Zn finger 186..206 CDD:275368 2/29 (7%)
C2H2 Zn finger 214..234 CDD:275368 6/19 (32%)
zf-H2C2_2 227..250 CDD:290200 7/24 (29%)
COG5048 <238..401 CDD:227381 49/155 (32%)
C2H2 Zn finger 242..262 CDD:275368 5/19 (26%)
zf-H2C2_2 255..279 CDD:290200 7/23 (30%)
C2H2 Zn finger 270..290 CDD:275368 5/19 (26%)
zf-H2C2_2 283..306 CDD:290200 7/22 (32%)
C2H2 Zn finger 298..318 CDD:275368 8/19 (42%)
zf-H2C2_2 310..335 CDD:290200 7/25 (28%)
C2H2 Zn finger 326..346 CDD:275368 7/19 (37%)
zf-H2C2_2 339..362 CDD:290200 8/23 (35%)
C2H2 Zn finger 354..374 CDD:275368 9/19 (47%)
zf-H2C2_2 367..390 CDD:290200 8/22 (36%)
C2H2 Zn finger 382..402 CDD:275368 2/7 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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