DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and LOC110437726

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	XP_021331500.1	Gene:	LOC110437726 / 110437726	-ID:	-	Length:	550	Species:	Danio rerio

Alignment Length:	284	Identity:	76/284 - (26%)
Similarity:	126/284 - (44%)	Gaps:	44/284 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 GKAETKQQAAKRARVQV-----------PAFKIVQA--TALKEPERQP-----GEEDECEEFMKE 141
            ||:|.|.|..|...:.:           |..::.:.  |..|..|.|.     .::..||..|:.
Zfish    59 GKSEKKTQKTKSHALFICCECGKSFSHKPKLEVHRRIHTGEKPYECQHCGKSFNQKQNCEAHMRI 123

  Fly   142 EMLDEEFQFSEPDDSMPSSEEEFFTETTEIPCHI-------------CGEMFSSQEVLERHIKAD 193
            ...::.::..:.|..        ||:...:..|:             ||:.|..::.|..|::..
Zfish   124 HTGEKPYKCQQCDMQ--------FTQKANLTVHMRVHTGEKTFNCQHCGKSFFQKQNLNVHMRVH 180

  Fly   194 TCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWDKKKYQ 258
            |.:|..|  |..||......:.|::|:.:|.|:....|:.|.|.|.||:....||.:|..:|.|:
Zfish   181 TGEKPYQ--CQQCGKSFSQPQNLNVHLKVHTGEKPFTCQECGKSFIHKQKFEAHMRIHTGEKLYK 243

  Fly   259 CDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKS 323
            |.:||:.||....:.:|:..| ||.....|:.|.:.|..|:..|.|:|.|..::| |.|..|.:|
Zfish   244 CLQCGKSFSQKTYLEDHMGIH-AEVKPFSCQQCGKSFNQKQKLKMHMRVHTGEKP-YSCQHCGRS 306

  Fly   324 FVDKYTLKVHKRVHQPVEKPESAE 347
            |....:|:||.|||.. |||.:.:
Zfish   307 FSQAPSLEVHMRVHTG-EKPYTCD 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	5/19 (26%)
		C2H2 Zn finger	231..251	CDD:275368	8/19 (42%)
		C2H2 Zn finger	259..308	CDD:275368	16/48 (33%)
		C2H2 Zn finger	288..303	CDD:275370	4/14 (29%)
		zf-C2H2	315..337	CDD:278523	9/21 (43%)
		C2H2 Zn finger	317..337	CDD:275368	8/19 (42%)
LOC110437726	XP_021331500.1	COG5048	73..485	CDD:227381	70/270 (26%)
		C2H2 Zn finger	76..96	CDD:275368	1/19 (5%)
		C2H2 Zn finger	104..124	CDD:275368	4/19 (21%)
		C2H2 Zn finger	132..152	CDD:275368	4/27 (15%)
		C2H2 Zn finger	160..180	CDD:275368	5/19 (26%)
		C2H2 Zn finger	188..208	CDD:275368	5/19 (26%)
		C2H2 Zn finger	216..236	CDD:275368	8/19 (42%)
		C2H2 Zn finger	244..264	CDD:275368	6/19 (32%)
		C2H2 Zn finger	272..292	CDD:275368	7/19 (37%)
		C2H2 Zn finger	300..320	CDD:275368	8/19 (42%)
		C2H2 Zn finger	328..348	CDD:275368	0/2 (0%)
		C2H2 Zn finger	356..376	CDD:275368
		C2H2 Zn finger	384..404	CDD:275368
		C2H2 Zn finger	412..432	CDD:275368
		C2H2 Zn finger	440..460	CDD:275368
		C2H2 Zn finger	468..488	CDD:275368
		C2H2 Zn finger	496..514	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910