DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and LOC108183935

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	XP_017211249.1	Gene:	LOC108183935 / 108183935	-ID:	-	Length:	358	Species:	Danio rerio

Alignment Length:	269	Identity:	69/269 - (25%)
Similarity:	112/269 - (41%)	Gaps:	48/269 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 KIVQATALKEPERQPGEEDECEEFMKEEMLDEEFQFSEPDDSMPSSEEEFFTETT---------- 169
            ||.:...:|:.:.|    ::.:..:.:|...::.:..|....|.:.|:...|:.|
Zfish    12 KIEETFTVKQEDLQ----EQTDLMLLKEKTHQQNEMEEIQQDMTTDEKPTLTKKTLSRGRHRKSK 72

  Fly   170 ---EIPCHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTELEC 231
               ...|..||:.||.:..|:.||:..|.:|:  .||..||....:...|.:||.:|.|:....|
Zfish    73 PSCNFSCKQCGKSFSQKPKLDVHIRDHTREKA--YTCKQCGKSFYNTRNLTVHMRIHTGERPYTC 135

  Fly   232 RYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEE------------- 283
            :.|.|.|....|:..||.:|..::.|.|.:||:.|..:..:..|:..|..|:
Zfish   136 QQCGKSFHKTGNLTVHMRIHTGERPYTCQQCGKSFQTTGNLTVHMRIHTGEKPYSCPQCGKSYNQ 200

  Fly   284 --------------NALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHK 334
                          ...:|..|.:.|..|:....|:|.|..::| |.|.:|.|||..|.|||.|.
Zfish   201 NSNLEVHMRTHNGGRTFVCTQCGKSFAQKQNLDLHMRIHTGEKP-YTCTECGKSFPYKSTLKHHM 264

  Fly   335 RVHQPVEKP 343
            .||.. |||
Zfish   265 IVHTG-EKP 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	6/19 (32%)
		C2H2 Zn finger	231..251	CDD:275368	7/19 (37%)
		C2H2 Zn finger	259..308	CDD:275368	13/75 (17%)
		C2H2 Zn finger	288..303	CDD:275370	4/14 (29%)
		zf-C2H2	315..337	CDD:278523	11/21 (52%)
		C2H2 Zn finger	317..337	CDD:275368	10/19 (53%)
LOC108183935	XP_017211249.1	C2H2 Zn finger	79..99	CDD:275368	8/19 (42%)
		C2H2 Zn finger	107..127	CDD:275368	6/19 (32%)
		zf-H2C2_2	119..144	CDD:316026	9/24 (38%)
		C2H2 Zn finger	135..155	CDD:275368	7/19 (37%)
		zf-H2C2_2	147..170	CDD:316026	8/22 (36%)
		C2H2 Zn finger	163..183	CDD:275368	5/19 (26%)
		COG5048	<187..346	CDD:227381	24/88 (27%)
		C2H2 Zn finger	191..211	CDD:275368	0/19 (0%)
		C2H2 Zn finger	219..239	CDD:275368	6/19 (32%)
		C2H2 Zn finger	247..267	CDD:275368	10/19 (53%)
		C2H2 Zn finger	275..295	CDD:275368
		C2H2 Zn finger	303..323	CDD:275368
		C2H2 Zn finger	330..350	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910