DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and si:cabz01054394.5

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	XP_009299258.1	Gene:	si:cabz01054394.5 / 101886221	ZFINID:	ZDB-GENE-161017-87	Length:	441	Species:	Danio rerio

Alignment Length:	284	Identity:	76/284 - (26%)
Similarity:	114/284 - (40%)	Gaps:	71/284 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 TALKEPERQPGEEDECEEFMKEEMLDEEFQFSEPDDS-MPSSEEEFFTE---------------- 167
            ||..:.||        ||...||.|..:.:::|.... ||..:|:.|||
Zfish     3 TAFIKKER--------EELTIEEPLSVKREYTEQQTGLMPLKKEQDFTEMDDNDQLENHHDLRKC 59

  Fly   168 -----------------TTEIPCHICGEMFSSQEVLERHIKADT---------CQKS-------- 198
                             |:.:.|..||:.|..::.|:.|:...|         |.||
Zfish    60 TQTERTSSQKTSPKRKPTSPVSCSQCGKSFDRKKKLDVHMTIHTGEKPFSCQQCGKSFTQKGNLK 124

  Fly   199 ---------EQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWDK 254
                     ...:|..||........|.:||.:|.|:....|..|.:.|:||.|:..||..|..:
Zfish   125 VHMGIHTGENSVSCQQCGKSFTQKINLKVHMRIHTGEKPYSCGQCGQSFTHKNNLNAHMRSHSGQ 189

  Fly   255 KKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPD 319
            |.:.|.:||.||:....:.||:..|..|: ...|..|.::|..|.:...|::.|..::| :||..
Zfish   190 KMFMCGQCGTRFTRKGGLENHMRIHTGEK-PFKCGQCGRRFTRKASLGTHMKIHTGEKP-FPCDQ 252

  Fly   320 CEKSFVDKYTLKVHKRVHQPVEKP 343
            |.|||..|.||..|||:|.. |:|
Zfish   253 CRKSFRRKVTLDSHKRIHTG-ERP 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	6/19 (32%)
		C2H2 Zn finger	231..251	CDD:275368	8/19 (42%)
		C2H2 Zn finger	259..308	CDD:275368	14/48 (29%)
		C2H2 Zn finger	288..303	CDD:275370	4/14 (29%)
		zf-C2H2	315..337	CDD:278523	12/21 (57%)
		C2H2 Zn finger	317..337	CDD:275368	11/19 (58%)
si:cabz01054394.5	XP_009299258.1	COG5048	<50..308	CDD:227381	60/229 (26%)
		C2H2 Zn finger	82..102	CDD:275368	6/19 (32%)
		C2H2 Zn finger	110..130	CDD:275368	3/19 (16%)
		C2H2 Zn finger	138..158	CDD:275368	6/19 (32%)
		C2H2 Zn finger	166..186	CDD:275368	8/19 (42%)
		C2H2 Zn finger	194..214	CDD:275368	7/19 (37%)
		C2H2 Zn finger	222..242	CDD:275368	5/19 (26%)
		C2H2 Zn finger	250..270	CDD:275368	11/19 (58%)
		C2H2 Zn finger	278..298	CDD:275368
		C2H2 Zn finger	334..350	CDD:275368
		C2H2 Zn finger	358..401	CDD:275368
		C2H2 Zn finger	409..426	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910