DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and Zfp958

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	XP_038944925.1	Gene:	Zfp958 / 100302405	RGDID:	2311392	Length:	495	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	68/244 - (27%)
Similarity:	108/244 - (44%)	Gaps:	25/244 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 TALKEPER-----QPGEEDECEE-------FMKEEML---DEEFQFSEPDDSM---PSSEEEFFT 166
            ::|:..||     :|.|.::|::       ..|.|..   ::.:..::.|.:.   .|..:...|
  Rat   200 SSLRRHERTHTGEKPYECNQCDKAFAYHSSLQKHERTHTGEKPYGCNQCDKAFACHSSLRKHERT 264

  Fly   167 ETTEIP--CHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTEL 229
            .|.|.|  |:.||:.|:....|.:|.:..|.:|..:  ||.||........|.:|...|.|:...
  Rat   265 HTGEKPYECNQCGKAFACHSTLRKHERIHTGEKPYE--CNQCGKAFSMQNTLRVHERTHTGEKPF 327

  Fly   230 ECRYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQ 294
            ||..|.|.|.....:..|..||..:|.::||:||:.|:.......|...|..|: ...|..|.:.
  Rat   328 ECNQCGKTFKLHSQLRIHKRVHTGEKPHECDQCGKTFACPSSFQKHKRVHSGEK-PYGCNQCDKA 391

  Fly   295 FKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKP 343
            |......:.|.|||..::| :.|..|.|:|....:|:||||.|.. |||
  Rat   392 FAIHSRLRKHERTHTGEKP-FKCNQCGKTFSQSNSLQVHKRTHTG-EKP 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	6/19 (32%)
		C2H2 Zn finger	231..251	CDD:275368	5/19 (26%)
		C2H2 Zn finger	259..308	CDD:275368	13/48 (27%)
		C2H2 Zn finger	288..303	CDD:275370	3/14 (21%)
		zf-C2H2	315..337	CDD:278523	9/21 (43%)
		C2H2 Zn finger	317..337	CDD:275368	9/19 (47%)
Zfp958	XP_038944925.1	KRAB	4..44	CDD:396083
		C2H2 Zn finger	80..97	CDD:275368
		C2H2 Zn finger	105..125	CDD:275368
		COG5048	129..490	CDD:227381	68/244 (28%)
		C2H2 Zn finger	133..153	CDD:275368
		C2H2 Zn finger	161..181	CDD:275368
		C2H2 Zn finger	189..209	CDD:275368	3/8 (38%)
		C2H2 Zn finger	217..237	CDD:275368	3/19 (16%)
		C2H2 Zn finger	245..265	CDD:275368	2/19 (11%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		C2H2 Zn finger	301..321	CDD:275368	6/19 (32%)
		C2H2 Zn finger	329..349	CDD:275368	5/19 (26%)
		C2H2 Zn finger	357..377	CDD:275368	6/19 (32%)
		C2H2 Zn finger	385..405	CDD:275368	5/19 (26%)
		C2H2 Zn finger	413..433	CDD:275368	9/19 (47%)
		C2H2 Zn finger	441..461	CDD:275368
		C2H2 Zn finger	469..489	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000