DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and znf1147

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_001108581.1	Gene:	znf1147 / 100141494	ZFINID:	ZDB-GENE-080218-13	Length:	260	Species:	Danio rerio

Alignment Length:	251	Identity:	76/251 - (30%)
Similarity:	118/251 - (47%)	Gaps:	27/251 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 KIVQATALKEPERQPGEEDECEEFMKEEM-----LDEEFQFSEPDDSMPSSEEEFFTETT----- 169
            ||.:...:|:.:.|   |......:|||.     :||::||.:|.: :.:.|:...|:.|
Zfish    12 KIEETFTVKQEDLQ---EQSDRMVLKEETHGQNEIDEKWQFEKPQE-ITTDEKPTLTKKTLSHGR 72

  Fly   170 --------EIPCHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGK 226
                    ...|.:|.:.||.:..|:.|::..|.:|  ..||..||......:.|..||.:|.|:
Zfish    73 PRKSKSGCNFSCKLCSKSFSQKSNLDVHMRVHTGEK--PYTCEQCGQSFSQKQCLKTHMRIHTGE 135

  Fly   227 TELECRYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVC 291
            ....|:.|.|.||.|.|:..||.||..:|.|.|::||:.||......:|:..|.. |....|:.|
Zfish   136 KPFSCKQCGKSFSQKPNLDIHMRVHTGEKPYTCEQCGKSFSQKQSFKSHMRIHTG-ERPYTCQQC 199

  Fly   292 HQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKPESAE 347
            .:.|:..|..:.|:|.|..::| :.|..|.||...|..|..|.||| .:|||.:.|
Zfish   200 GKSFRHARNLEVHMRIHTGEKP-FSCKQCRKSLSKKLNLIAHMRVH-TMEKPYTCE 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	6/19 (32%)
		C2H2 Zn finger	231..251	CDD:275368	9/19 (47%)
		C2H2 Zn finger	259..308	CDD:275368	14/48 (29%)
		C2H2 Zn finger	288..303	CDD:275370	4/14 (29%)
		zf-C2H2	315..337	CDD:278523	8/21 (38%)
		C2H2 Zn finger	317..337	CDD:275368	8/19 (42%)
znf1147	NP_001108581.1	zf-C2H2	82..104	CDD:278523	6/21 (29%)
		C2H2 Zn finger	84..104	CDD:275368	6/19 (32%)
		COG5048	<86..257	CDD:227381	59/173 (34%)
		zf-H2C2_2	96..121	CDD:290200	8/26 (31%)
		C2H2 Zn finger	112..132	CDD:275368	6/19 (32%)
		zf-H2C2_2	125..149	CDD:290200	9/23 (39%)
		C2H2 Zn finger	140..160	CDD:275368	9/19 (47%)
		zf-H2C2_2	152..177	CDD:290200	11/24 (46%)
		C2H2 Zn finger	168..188	CDD:275368	6/19 (32%)
		zf-H2C2_2	180..205	CDD:290200	6/25 (24%)
		C2H2 Zn finger	196..216	CDD:275368	6/19 (32%)
		zf-H2C2_2	208..230	CDD:290200	6/22 (27%)
		C2H2 Zn finger	224..244	CDD:275368	8/19 (42%)
		zf-H2C2_2	236..259	CDD:290200	9/19 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910