DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and si:ch211-161m3.6

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_001314790.1	Gene:	si:ch211-161m3.6 / 100005838	ZFINID:	ZDB-GENE-161017-36	Length:	295	Species:	Danio rerio

Alignment Length:	264	Identity:	77/264 - (29%)
Similarity:	113/264 - (42%)	Gaps:	56/264 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 EDECEEFMKEE-----MLDEEFQFSEPDDSMPSSEE-----------------EFFT-------- 166
            ::|||:...|:     |.|.|    |..|.:|..||                 .|.|
Zfish     5 KEECEDIKTEDVFIVKMEDAE----EHTDPLPVKEESQELDEVEEKGPFENYQHFVTGGQSFHRA 65

  Fly   167 ---------ETTEIP------CHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVL 216
                     :..||.      |..||:.|:.:..|.||::..|.:|  ..:|.:||........|
Zfish    66 RTDRTSSQEKVQEIDPISYFICFQCGKGFTQKGSLNRHMRTHTGEK--PYSCPLCGKSFNQHGNL 128

  Fly   217 DLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDA 281
            ::||.:|.|:|...|:.|.|.||.|.|:..||.||..:..:.|.:||..|:....:..|:..|..
Zfish   129 EVHMGVHSGETPFACQQCGKSFSRKGNLRYHMRVHTGECPFTCQQCGISFTAKGSLTRHMRIHTG 193

  Fly   282 EENALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVH---QPVEKP 343
             |....|..|.:.|:...:.|.|:|||..::| |.|..|.|||.....||||.|:|   :|.|.|
Zfish   194 -ERPYTCSECGESFEQHGSLKVHMRTHTGEKP-YTCQQCGKSFDQHGNLKVHLRIHTGEKPYECP 256

  Fly   344 ESAE 347
            :.|:
Zfish   257 QCAK 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	6/19 (32%)
		C2H2 Zn finger	231..251	CDD:275368	9/19 (47%)
		C2H2 Zn finger	259..308	CDD:275368	13/48 (27%)
		C2H2 Zn finger	288..303	CDD:275370	3/14 (21%)
		zf-C2H2	315..337	CDD:278523	11/21 (52%)
		C2H2 Zn finger	317..337	CDD:275368	10/19 (53%)
si:ch211-161m3.6	NP_001314790.1	COG5048	<65..234	CDD:227381	51/172 (30%)
		zf-C2H2	85..107	CDD:278523	7/21 (33%)
		C2H2 Zn finger	87..107	CDD:275368	7/19 (37%)
		zf-H2C2_2	99..124	CDD:290200	8/26 (31%)
		C2H2 Zn finger	115..135	CDD:275368	6/19 (32%)
		zf-H2C2_2	127..152	CDD:290200	10/24 (42%)
		C2H2 Zn finger	143..163	CDD:275368	9/19 (47%)
		zf-H2C2_2	155..179	CDD:290200	8/23 (35%)
		C2H2 Zn finger	171..191	CDD:275368	5/19 (26%)
		zf-H2C2_2	183..208	CDD:290200	6/25 (24%)
		C2H2 Zn finger	199..219	CDD:275368	6/19 (32%)
		zf-H2C2_2	211..236	CDD:290200	12/25 (48%)
		C2H2 Zn finger	227..247	CDD:275368	10/19 (53%)
		zf-H2C2_2	239..264	CDD:290200	10/22 (45%)
		C2H2 Zn finger	255..271	CDD:275368	2/6 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910