DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ZIPIC and CG1647

DIOPT Version :9

Sequence 1:	NP_651765.1	Gene:	ZIPIC / 43566	FlyBaseID:	FBgn0039740	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_651636.1	Gene:	CG1647 / 43401	FlyBaseID:	FBgn0039602	Length:	1222	Species:	Drosophila melanogaster

Alignment Length:	454	Identity:	85/454 - (18%)
Similarity:	147/454 - (32%)	Gaps:	157/454 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CCICQF---------SVRVPKDIHTDTVGHPPVLISELVLQCTRGTNYVLTEESSTICKKCCEKL 58
            |.||:.         .:.:|.:  .||:......:|:.:.:....|..|..:...|||.:|.:|:
  Fly    17 CTICRLCGIDNPGKVPILLPNE--EDTIDLDEPRMSQKIYELVGFTVSVDDKMPQTICSQCVDKI 79

  Fly    59 ARYHKSIQIARKLRGEILELIHSPYMSKDHKQTSYKEDDLDRETTISKFDGNIEEAQQQDEEEQE 123
            ..::           |..|:.::     .:|||.                 |:...:|
  Fly    80 NDFY-----------EFREMCYA-----TNKQTR-----------------NLLGLKQ------- 104

  Fly   124 LESVGTTVTLVGPAGIVE--EVAEEEHTFIIKQSEEEDEFHSVDLELDIDNEIIINEEEAHEVEE 186
                      :.||.:::  .:.:||...                     :..:.......:.||
  Fly   105 ----------IEPARLIDLKRIVKEERPI---------------------SGAVGKRGRKRKGEE 138

  Fly   187 VAHEIEEVAHEIEEEDLLPHDKQEAQEEDFF-----KEDTMSDFDEHLDGAIEYIISDGEDQEQD 246
            ...:...|..::::|..:.|.||:.|.....     :|..:.|                |..|||
  Fly   139 SWPKNNNVKPQVKKESFVWHKKQKLQPSQITSLVSKREPEIKD----------------EPAEQD 187

  Fly   247 N------ESSGEYTVNIQCPSCPEKFSSRRAYNVHTKREHFPG---YVCDQCGKTLQSYSGFIGH 302
            .      :.:|..::   |..|.|||.|:...:.|....|.|.   |:|:.|.:|..:.|....|
  Fly   188 TSLKGPPKKAGRKSI---CSVCGEKFLSKELADEHKSLVHVPSIPRYICNACNQTHHNQSDIRAH 249

  Fly   303 LQNHEPVK-QFACPVCPERFSRKFRLKHHMAWHSGETPYQ-------CDVCSKRFV-------HK 352
            ...|:..| .:.||:|....:..:....|:..|:..||.|       |.:|.|.||       |:
  Fly   250 QLWHKLSKTPYKCPLCESSVANAYAFTRHLREHTPPTPVQLLVLDRECPLCKKTFVTNFFYNTHR 314

  Fly   353 VALYKHKMIHDSETKRLECQVCGFKTRTKAHLERHMRSHTGDKPFACPVCNKRFSQMYNMKAHL 416
            .|:.|.|           |..|.....|:|...||           .|.|.|.:   .|...|:
  Fly   315 CAIRKRK-----------CGGCSRTLNTEAAYMRH-----------APTCPKIY---LNHSKHI 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	5/19 (26%)
		C2H2 Zn finger	314..334	CDD:275368	4/19 (21%)
		zf-H2C2_2	327..351	CDD:290200	10/37 (27%)
		C2H2 Zn finger	342..391	CDD:275368	15/55 (27%)
		zf-H2C2_2	383..408	CDD:290200	5/24 (21%)
		C2H2 Zn finger	399..419	CDD:275368	5/18 (28%)
		C2H2 Zn finger	432..449	CDD:275368
CG1647	NP_651636.1	zf-AD	19..99	CDD:285071	18/114 (16%)
		C2H2 Zn finger	203..224	CDD:275368	7/20 (35%)
		C2H2 Zn finger	233..253	CDD:275368	5/19 (26%)
		C2H2 Zn finger	262..282	CDD:275368	4/19 (21%)
		C2H2 Zn finger	297..314	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100