DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZIPIC and Blimp-1

DIOPT Version :9

Sequence 1:	NP_651765.1	Gene:	ZIPIC / 43566	FlyBaseID:	FBgn0039740	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001261442.1	Gene:	Blimp-1 / 38638	FlyBaseID:	FBgn0035625	Length:	1216	Species:	Drosophila melanogaster

Alignment Length:	181	Identity:	56/181 - (30%)
Similarity:	90/181 - (49%)	Gaps:	13/181 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   283 GYVCDQCGKTL-------QSYSGFIGHLQNHEPVKQFACPVCPERFSRKFRLKHHMAWHSGETPY 340
            |..|.:.|..|       :.|......|:..:....:.|.||.:.|.:...||.|:..||||.|:
  Fly   854 GNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPF 918

  Fly   341 QCDVCSKRFVHKVALYKHKMIHDSETKRLECQVCGFKTRTKAHLERHMRSHTGDKPFACPVCNKR 405
            :|:||:|.|.....|.||.::|..| |..:|.:|..:..:.::|:.|:|.|:|.||:||.:|.::
  Fly   919 KCNVCTKSFTQLAHLQKHHLVHTGE-KPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQK 982

  Fly   406 FSQMYNMKAHLREHESPGTNRHRRFHCSKCTHTFINEQNYDAHVQRDDCTP 456
            |:|..::|.|.|.|    || .|.:.|..|...:|:......|.:...|.|
  Fly   983 FTQFVHLKLHKRLH----TN-DRPYVCQGCDKKYISASGLRTHWKTTSCKP 1028

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	5/26 (19%)
		C2H2 Zn finger	314..334	CDD:275368	7/19 (37%)
		zf-H2C2_2	327..351	CDD:290200	13/23 (57%)
		C2H2 Zn finger	342..391	CDD:275368	16/48 (33%)
		zf-H2C2_2	383..408	CDD:290200	11/24 (46%)
		C2H2 Zn finger	399..419	CDD:275368	7/19 (37%)
		C2H2 Zn finger	432..449	CDD:275368	3/16 (19%)
Blimp-1	NP_001261442.1	SET	133..260	CDD:214614
		C2H2 Zn finger	892..912	CDD:275368	7/19 (37%)
		zf-H2C2_2	904..929	CDD:290200	13/24 (54%)
		C2H2 Zn finger	920..940	CDD:275368	8/19 (42%)
		zf-H2C2_2	932..957	CDD:290200	8/25 (32%)
		C2H2 Zn finger	948..968	CDD:275368	5/19 (26%)
		zf-H2C2_2	960..985	CDD:290200	11/24 (46%)
		C2H2 Zn finger	976..996	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1004..1023	CDD:275368	4/18 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457163
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930