DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZIPIC and Cf2

DIOPT Version :9

Sequence 1:	NP_651765.1	Gene:	ZIPIC / 43566	FlyBaseID:	FBgn0039740	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster

Alignment Length:	344	Identity:	84/344 - (24%)
Similarity:	134/344 - (38%)	Gaps:	72/344 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 IEEAQQQDEEEQ--ELESVGTTVTL-VGPAGIVEE---------------------VAEEEHTFI 151
            |..|.||..|.:  :..|:.||..| .|..|.:|:                     ..||:|...
  Fly   165 IHSATQQPNEYKCTQCGSICTTAMLAAGQQGFMEQQEAAVTPDDQLPAMAPRDMRLTPEEQHHQQ 229

  Fly   152 IKQSEEEDEFHSVDLELDIDNEIIINEEEAHEVEEVAHEIEEVAHEIEEEDLLPHDKQEAQEEDF 216
            ..|:|...:......:.....:..:.|::..|::|.|.: ::|.|..:::||       |.::..
  Fly   230 QLQAEHHHQQQHQQQQQQQQQQQELLEQQQREMQEQAQQ-QQVHHHQQDQDL-------AGDQVA 286

  Fly   217 FKEDTMS-DFDEHLDGAIEYIISDGE----DQEQDNESSGEYTVNIQCPSCPEKFSSRRAYNVHT 276
            .|...:: ..:::.:|..  |:|..:    ::......||: .||    |.|       .|.:..
  Fly   287 LKVPPLTVKLNKNANGGA--IVSHPQVIIKEEPLSLSDSGD-VVN----SVP-------VYAIQA 337

  Fly   277 KREHFPGYVCDQCGKTL---QSYSGFIGHLQNHEPVKQFACPVCPERFSRKFRLKHHMAWHSGET 338
            .    ||.........|   |:....:.|...|:      ||.||:.|.....|..|...|:||.
  Fly   338 N----PGVPAPASSGVLVGTQTVPADLAHKIRHK------CPDCPKTFKTPGTLAMHRKIHTGEA 392

  Fly   339 -------PYQCDVCSKRFVHKVALYKHKMIHDSETKRLECQVCGFKTRTKAHLERHMRSHTGDKP 396
                   ||.|..|.|.|.....|.:|..||..| |...|..|......|.:|.:|:|:|||:||
  Fly   393 DATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGE-KPFHCGYCEKSFSVKDYLTKHIRTHTGEKP 456

  Fly   397 FACPVCNKRFSQMYNMKAH 415
            :.||.|:|||:|...:..|
  Fly   457 YTCPYCDKRFTQRSALTVH 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	3/22 (14%)
		C2H2 Zn finger	314..334	CDD:275368	7/19 (37%)
		zf-H2C2_2	327..351	CDD:290200	11/30 (37%)
		C2H2 Zn finger	342..391	CDD:275368	16/48 (33%)
		zf-H2C2_2	383..408	CDD:290200	14/24 (58%)
		C2H2 Zn finger	399..419	CDD:275368	8/17 (47%)
		C2H2 Zn finger	432..449	CDD:275368
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	41/113 (36%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		C2H2 Zn finger	403..423	CDD:275368	6/19 (32%)
		C2H2 Zn finger	431..451	CDD:275368	6/19 (32%)
		zf-H2C2_2	443..468	CDD:316026	14/24 (58%)
		C2H2 Zn finger	459..480	CDD:275368	8/17 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468404
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930