DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZIPIC and CG42726

DIOPT Version :9

Sequence 1:	NP_651765.1	Gene:	ZIPIC / 43566	FlyBaseID:	FBgn0039740	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	240	Identity:	62/240 - (25%)
Similarity:	112/240 - (46%)	Gaps:	18/240 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 MSDFDEHLDGAIEYIISDGEDQEQDNESSGEYTVNI-----QCPSCPEKFSSR--RAYNVHTKRE 279
            ::|..:.|:..:...:...|.||....:|.:..:.:     .|..|.:.|.||  :.|::....:
  Fly    32 VADVSDCLECRVARSVDIQETQETQARTSADKRIIVTDKGYHCTVCNKDFRSRTQQYYHLTCGND 96

  Fly   280 HFPGYVCDQCGKTLQSYSGFIGHLQNHEPVKQFACPVCPERFSRKFRLKHHMAWHSGETPYQCDV 344
            ....:.|.:||:...:.|....||.:||...:.:|.||.:.|.:...|:.||..|:.| .:.|.:
  Fly    97 LLKKFNCKECGRRFATSSHLKYHLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQE-KHLCPI 160

  Fly   345 CSKRFVHKVALYKHKMIHDSETKRLECQVCGFKTRTKAHLERHMRSHTGDK---PFACPVCNKRF 406
            |.|.|..|.:|..|..||.....:.:|::|....:.||:|.:|:|.|  ||   ...|.||.|.|
  Fly   161 CQKVFRRKSSLASHLAIHSDLGLQFKCELCSKHFQNKANLNQHLRKH--DKNNIRHMCKVCQKSF 223

  Fly   407 SQMYNMKAHLREHESPGTNRHRRFHCSKCTHTFINEQNYDAHVQR 451
            .:...::.|::.|    :||.|: .||.|..::.:......|:::
  Fly   224 LRQTTLRLHMKRH----SNRERQ-SCSLCGKSYNDPDALGRHLRQ 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..334	CDD:275368	7/19 (37%)
		zf-H2C2_2	327..351	CDD:290200	9/23 (39%)
		C2H2 Zn finger	342..391	CDD:275368	16/48 (33%)
		zf-H2C2_2	383..408	CDD:290200	11/27 (41%)
		C2H2 Zn finger	399..419	CDD:275368	6/19 (32%)
		C2H2 Zn finger	432..449	CDD:275368	3/16 (19%)
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	6/19 (32%)
		C2H2 Zn finger	103..123	CDD:275368	6/19 (32%)
		COG5048	<112..288	CDD:227381	47/160 (29%)
		C2H2 Zn finger	131..151	CDD:275368	7/19 (37%)
		Chordopox_A33R	151..>254	CDD:283591	34/110 (31%)
		C2H2 Zn finger	158..178	CDD:275368	7/19 (37%)
		C2H2 Zn finger	187..207	CDD:275368	7/19 (37%)
		C2H2 Zn finger	216..236	CDD:275368	6/19 (32%)
		C2H2 Zn finger	244..264	CDD:275368	4/20 (20%)
		C2H2 Zn finger	272..290	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468405
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930