DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZIPIC and znf-782

DIOPT Version :9

Sequence 1:	NP_651765.1	Gene:	ZIPIC / 43566	FlyBaseID:	FBgn0039740	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_500033.1	Gene:	znf-782 / 190310	WormBaseID:	WBGene00021931	Length:	662	Species:	Caenorhabditis elegans

Alignment Length:	353	Identity:	90/353 - (25%)
Similarity:	127/353 - (35%)	Gaps:	112/353 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 DEFHSVDLELDIDNEIIINEEEAHEVE-EVAHEIEEVAHEIEEEDLLPHDKQEAQEEDFFKEDTM 222
            |:.|..|.|          |||..|.| |:..|.||...|:||.
Worm    17 DDIHMKDPE----------EEEFEEYEDELLEEEEEFDEELEEL--------------------- 50

  Fly   223 SDFDEHLDGAIEYIISDG--EDQEQDNESSGEY-TVNIQCPSCPEKFSSRRAYNVHTKREHFPGY 284
                |:.|.| ..::|.|  ......|.|.|.. .:.:|.||  :...|..:.....::.|
Worm    51 ----ENSDSA-SSLVSAGSPHGSSSSNGSHGSSPPLQVQSPS--QGSGSSGSPTGQPEKRH---- 104

  Fly   285 VCDQCGKTLQSYSGFIGHLQNHEPVKQFACPVCPERFSRKFRLKHHMAWHSGETPYQCDVCSKRF 349
            :|..|||....:|....|.::|...|.:.|..|.:.|::|..|:.|...|:||.||:|..|.|.|
Worm   105 ICTVCGKGFSYFSILESHKRSHTGEKPYNCHFCQKTFAQKATLQVHERTHTGERPYKCRYCEKTF 169

  Fly   350 -------VHK----------------------VALYKHKMIHDSETKRLECQVC----GFKTRTK 381
                   ||:                      .|||.||..|..:|.|  |..|    ..|...|
Worm   170 AQYGTKTVHEKSAHLGIRNYKCPKCDKLLSSPSALYTHKKTHGDKTFR--CDFCPKTFALKNYLK 232

  Fly   382 AH--------------------------LERHMRSHTGDKPFACPVCNKRFSQMYNMKAHLREHE 420
            .|                          |:.|:|:|||::|:.|..|.|.|:...|:::|.|.|.
Worm   233 LHVKQVHEQNERKHVCVYCNKGFAYAGSLQVHVRTHTGERPYVCKFCPKAFASQGNLQSHERTHT 297

  Fly   421 SPGTNRHRRFHCSKCTHTFINEQNYDAH 448
            .     .|.:.|..|..|||.:....||
Worm   298 G-----ERPYSCQFCQRTFIQKSQLTAH 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..334	CDD:275368	6/19 (32%)
		zf-H2C2_2	327..351	CDD:290200	11/30 (37%)
		C2H2 Zn finger	342..391	CDD:275368	22/107 (21%)
		zf-H2C2_2	383..408	CDD:290200	12/50 (24%)
		C2H2 Zn finger	399..419	CDD:275368	7/19 (37%)
		C2H2 Zn finger	432..449	CDD:275368	7/17 (41%)
znf-782	NP_500033.1	C2H2 Zn finger	106..126	CDD:275368	6/19 (32%)
		zf-H2C2_2	119..143	CDD:290200	6/23 (26%)
		C2H2 Zn finger	134..154	CDD:275368	6/19 (32%)
		zf-H2C2_2	147..171	CDD:290200	11/23 (48%)
		C2H2 Zn finger	162..180	CDD:275368	6/17 (35%)
		COG5048	<187..404	CDD:227381	36/141 (26%)
		C2H2 Zn finger	191..211	CDD:275370	5/19 (26%)
		C2H2 Zn finger	218..239	CDD:275368	5/20 (25%)
		C2H2 Zn finger	248..268	CDD:275368	3/19 (16%)
		zf-H2C2_2	260..285	CDD:290200	11/24 (46%)
		C2H2 Zn finger	276..296	CDD:275368	7/19 (37%)
		zf-H2C2_2	288..313	CDD:290200	9/29 (31%)
		C2H2 Zn finger	304..324	CDD:275368	7/17 (41%)
		C2H2 Zn finger	386..403	CDD:275368
		C2H2 Zn finger	424..441	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000