Protein Alignment ZIPIC and ZFP1

DIOPT Version :10

• Sequence 1: NP_651765.1
• Gene: ZIPIC / 43566
• FlyBaseID: FBgn0039740
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: XP_047289624.1
• Gene: ZFP1 / 162239
• HGNCID: 23328
• Length: 455
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 122/467 - (26%)
• Similarity: 185/467 - (39%)
• Gaps: 78/467 - (16%)

  Fly     9 SVRVPKD--IHTDTVGHPPVLISELVLQCTRGTNYVLTEESSTICKKCCEKLARY---HKSIQIA 68
            |||...|  ||       ||..|.::.....||..|  ::...|..:....:..|   |.|:.:.
Human    31 SVRCSPDPRIH-------PVTSSVIISVAIPGTREV--QKGKVISLRSHNPVVLYFCLHSSLPLP 86

  Fly    69 RKLRGEILELI--HSPYMSKDHKQTSYKEDDLDRETTISKFDGNIEE-------AQQQDEEEQEL 124
            :....|.:..:  ....|.:||:    ..|:..|:..|.|....|||       |...:.:...|
Human    87 KTAENEQIPEVWKADDQMERDHR----NPDEQARQFLILKNQTPIEERGDLFGKALNLNTDFVSL 147

  Fly   125 ESVGTTVTLVGPA-GIVEEVAEEEHTFIIKQSEEEDEFHSVDLELDIDNEIIINEEEAH---EVE 185
            ..|.....|.... ....::.....::..||::|.:||....|.|        .:|:.|   |..
Human   148 RQVPYKYDLYEKTLKYNSDLLNSNRSYAGKQTDECNEFGKALLYL--------KQEKTHSGVEYS 204

  Fly   186 EVAHEIEEVAHEIEEEDLLPHDKQEAQEEDFFKEDTMSDFDEHLDGAIEY---IISDGEDQEQDN 247
            |.....:.::|:..   :..|.|.:...:.|        ...:.|.|..:   :||      ...
Human   205 EYNKSGKALSHKAA---IFKHQKIKNLVQPF--------ICTYCDKAFSFKSLLIS------HKR 252

  Fly   248 ESSGEYTVNIQCPSCPEKFSSR----RAYNVHTKREHFPGYVCDQCGKTLQSYSGFIGHLQNHEP 308
            ..:||..  .:|..|.:.||.:    :...:||..:.|.   |.:|||.....|..|.|.:.|..
Human   253 IHTGEKP--YECNVCKKTFSHKANLIKHQRIHTGEKPFE---CPECGKAFTHQSNLIVHQRAHME 312

  Fly   309 VKQFACPVCPERFSRKFRLKHHMAWHSGETPYQCDVCSKRFVHKVALYKHKMIHDSETKRLECQV 373
            .|.:.|..|.:.|::||.|..|...|:||.||:|:.|:|.|..|..|..|:.||..| ||.||..
Human   313 KKPYECSECGKTFAQKFELTTHQRIHTGERPYECNECAKTFFKKSNLIIHQKIHTGE-KRYECSE 376

  Fly   374 CGFKTRTKAHLERHMRSHTGDKPFACPVCNKRFSQMYNMKAHLREH--ESPGTNRHRRFHCSKCT 436
            ||......:.|..|||:|||:||:.|..|.|.|||...::.|||.|  |.|       :.||:|.
Human   377 CGKSFIQNSQLIIHMRTHTGEKPYECTECGKTFSQRSTLRLHLRIHTGEKP-------YECSECG 434

  Fly   437 HTFINEQNYDAH 448
            ..|..:.....|
Human   435 KAFSRKSRLSVH 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	7/19 (37%)
		C2H2 Zn finger	314..334	CDD:275368	7/19 (37%)
		SFP1	<336..419	CDD:227516	38/82 (46%)
		C2H2 Zn finger	342..391	CDD:275368	20/48 (42%)
		zf-H2C2_2	383..408	CDD:463886	13/24 (54%)
		C2H2 Zn finger	399..419	CDD:275368	9/19 (47%)
		C2H2 Zn finger	432..449	CDD:275368	5/17 (29%)
ZFP1	XP_047289624.1	COG5048	<194..451	CDD:227381	84/283 (30%)
		C2H2 Zn finger	210..226	CDD:275368	3/18 (17%)
		C2H2 Zn finger	234..254	CDD:275368	4/25 (16%)
		C2H2 Zn finger	262..282	CDD:275368	4/19 (21%)
		C2H2 Zn finger	290..310	CDD:275368	7/19 (37%)
		C2H2 Zn finger	318..338	CDD:275368	7/19 (37%)
		C2H2 Zn finger	346..366	CDD:275368	7/19 (37%)
		C2H2 Zn finger	374..394	CDD:275368	7/19 (37%)
		C2H2 Zn finger	402..422	CDD:275368	9/19 (47%)
		C2H2 Zn finger	430..450	CDD:275368	5/17 (29%)