DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZIPIC and Zfp692

DIOPT Version :9

Sequence 1:	NP_651765.1	Gene:	ZIPIC / 43566	FlyBaseID:	FBgn0039740	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001035776.1	Gene:	Zfp692 / 103836	MGIID:	2144276	Length:	531	Species:	Mus musculus

Alignment Length:	367	Identity:	96/367 - (26%)
Similarity:	137/367 - (37%)	Gaps:	92/367 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 EEAQ----QQDEEEQEL---ESVGTTVTLVGPAGIVEEVAEEEHTFIIKQSEEEDEFHS------ 163
            :|||    :|.|..||.   ..|.:.:.:..|.|..::|.|||     ::.|||:|..|
Mouse   154 QEAQGLECEQRERTQETRLSRRVDSPLEIDPPLGEDQDVEEEE-----EEEEEEEELLSDASPWT 213

  Fly   164 -----VDLELDIDN---EIIINEEEAHEVEEVAHEIE---EVAHEIEEEDLLPHDKQEAQEEDFF 217
                 .|.|.|:..   ..:.:..:..||..|...:.   .|...:...|.|..|.:...|   .
Mouse   214 YSSSPDDSEPDVPRPPPSPVTHTPKEGEVSPVPATLPTPCAVLASVGSPDALTSDTEVRLE---L 275

  Fly   218 KEDTMSDFDEHLDGAIEYIISDG-EDQEQDNESSGEYTVNI--------------QC--PSCPEK 265
            ........:.|:..::|   |.| :.|...|.:..|.|..|              .|  |.|...
Mouse   276 SRTPQVPAELHMTESLE---SPGSQAQSAPNPTWDEDTAQIGLRRIRKAAKRELMPCDFPGCGRI 337

  Fly   266 FSSRRAYNVHTKREHFPGYVCDQCGKTLQSYSGFIGHLQNHEPVKQFAC--PVCPERFSRKFRLK 328
            ||:|:..|.|.|.:|.                        |:  |.|.|  |.|.:.|:.|..||
Mouse   338 FSNRQYLNHHKKYQHI------------------------HQ--KSFCCPEPACGKSFNFKKHLK 376

  Fly   329 HHMAWHSGETPYQCDVCSKRFVHKVALYKHKMIHDSETKRLECQVCGFKTRTKAHLERHMRSHTG 393
            .|:..||....|.|:.|::.|.....|..|:.||..| |.|:|::|||..|.||.|..|.|.|..
Mouse   377 EHVKLHSDTRDYICEFCARSFRTSSNLVIHRRIHTGE-KPLQCEICGFTCRQKASLNWHRRKHAE 440

  Fly   394 DKP---FACPVCNKRFSQMYNMKAH--------LREHESPGT 424
            ...   |.|..|.|||.:..::.||        |...|.||:
Mouse   441 TAAALRFPCEFCGKRFEKPDSVVAHCSKSHPALLPAQEPPGS 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	0/19 (0%)
		C2H2 Zn finger	314..334	CDD:275368	8/21 (38%)
		zf-H2C2_2	327..351	CDD:290200	9/23 (39%)
		C2H2 Zn finger	342..391	CDD:275368	20/48 (42%)
		zf-H2C2_2	383..408	CDD:290200	10/27 (37%)
		C2H2 Zn finger	399..419	CDD:275368	8/27 (30%)
		C2H2 Zn finger	432..449	CDD:275368
Zfp692	NP_001035776.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	155..249		25/98 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	287..307		5/22 (23%)
		zf-C2H2_8	328..406	CDD:292531	28/103 (27%)
		C2H2 Zn finger	360..382	CDD:275368	8/21 (38%)
		COG5048	383..>436	CDD:227381	21/53 (40%)
		C2H2 Zn finger	390..410	CDD:275368	5/19 (26%)
		zf-H2C2_2	402..427	CDD:290200	11/25 (44%)
		C2H2 Zn finger	418..438	CDD:275368	10/19 (53%)
		C2H2 Zn finger	449..465	CDD:275368	5/15 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	474..531		4/9 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100