DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZIPIC and znf276

DIOPT Version :9

Sequence 1:	NP_651765.1	Gene:	ZIPIC / 43566	FlyBaseID:	FBgn0039740	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	XP_002933710.1	Gene:	znf276 / 100486887	XenbaseID:	XB-GENE-983669	Length:	570	Species:	Xenopus tropicalis

Alignment Length:	355	Identity:	92/355 - (25%)
Similarity:	136/355 - (38%)	Gaps:	100/355 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 GIVEEVAE--EEHTFIIK----------QSEEE---------DEFHSVDLELDIDNEIIINEEEA 181
            ||::.|.|  ..|.:|::          |.|||         :..|.::.....|:|  .|..:.
Frog   200 GIIQAVWECGGGHDYIMQPDSDCISSPAQPEEEMSPEQGLSGNGIHRINTRTIPDSE--YNPPDR 262

  Fly   182 HEVEEVAHEIEEVAHEIEEE-----DLLPHDKQEAQE--------EDFFKEDTMSDFDEHLDGAI 233
            .....|..:...|.:.|.:.     .|...|..:.|:        .|..||| .||
Frog   263 INTASVLLDTCVVVNHITQNRTPSPPLAAPDSSQGQDCRNSTLASNDHSKED-CSD--------- 317

  Fly   234 EYIISDGEDQEQDNESSGEYTVNIQCPSCPEKFS---SRRAYNVHTKRE--------HF------ 281
               :|||:.|.|:....|      |.||..:.|.   ::|  |...|||        .|
Frog   318 ---LSDGDFQSQEEGEPG------QQPSSDDSFEPCIAKR--NPQKKREPRKSQKLTEFREKKKP 371

  Fly   282 ---PG--------------YVC--DQCGKTLQSYSGFIGHL-QNHEPVKQFAC--PVCPERFSRK 324
               ||              |.|  ..|....:...|...|: ::||.|::..|  |.|.:.|...
Frog   372 GPKPGWKKIKREREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMID 436

  Fly   325 FRLKHHMAW-HSGETPYQCDVCSKRFVHKVALYKHKMIHDSETKRLECQVCGFKTRTKAHLERHM 388
            ..|:.|:.. |:.|..:.||.|.:.|..:..|..|:|.| |..|.|:|:||||:.|.:|.|:.||
Frog   437 RYLQRHVKLIHTEERNHICDQCGQAFKQRKHLSVHQMRH-SGAKPLQCEVCGFQCRQRASLKYHM 500

  Fly   389 RSH--TGDKPFACPVCNKRFSQMYNMKAHL 416
            ..|  ..|..|||..|.|||.:.:|:..|:
Frog   501 TKHKAEADLEFACDQCAKRFEKAHNLNVHM 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	4/22 (18%)
		C2H2 Zn finger	314..334	CDD:275368	6/22 (27%)
		zf-H2C2_2	327..351	CDD:290200	8/24 (33%)
		C2H2 Zn finger	342..391	CDD:275368	21/48 (44%)
		zf-H2C2_2	383..408	CDD:290200	12/26 (46%)
		C2H2 Zn finger	399..419	CDD:275368	7/18 (39%)
		C2H2 Zn finger	432..449	CDD:275368
znf276	XP_002933710.1	SFP1	<320..476	CDD:227516	41/164 (25%)
		C2H2 Zn finger	427..447	CDD:275368	5/19 (26%)
		C2H2 Zn finger	455..475	CDD:275368	7/19 (37%)
		C2H2 Zn finger	483..503	CDD:275368	10/19 (53%)
		C2H2 Zn finger	513..530	CDD:275368	6/16 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100