DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZIPIC and si:dkeyp-2e4.2

DIOPT Version :9

Sequence 1:	NP_651765.1	Gene:	ZIPIC / 43566	FlyBaseID:	FBgn0039740	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001122042.1	Gene:	si:dkeyp-2e4.2 / 100149164	ZFINID:	ZDB-GENE-030131-9307	Length:	251	Species:	Danio rerio

Alignment Length:	202	Identity:	58/202 - (28%)
Similarity:	95/202 - (47%)	Gaps:	34/202 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 DQEQDNESS----------------GEYTVNIQCPSCPEKFSSR----RAYNVHTKREHFPGYVC 286
            ||..|..||                ||   ::.|..|..:|.|.    |...:||..   ..|:|
Zfish    50 DQTSDQSSSDTDTEDELPISTSPTPGE---DLICKLCGSEFGSNISMVRHMRIHTGE---TPYIC 108

  Fly   287 DQCGKTLQSYSGFIGHLQNH-----EPVKQFACPVCPERFSRKFRLKHHMAWHSGETPYQCDVCS 346
            :.|||..:.......|.:.|     :..|:.:|..|..:|:....|:.|:..|.||.|:.|..|.
Zfish   109 EVCGKGFKRQGWLKEHFRVHTGNKRKREKRLSCDQCEMKFNSSTALRSHLNKHRGERPFACVQCD 173

  Fly   347 KRFVHKVALYKHKMIHDSET-KRLECQVCGFKTRTKAHLERHMRSHTGDKPFACPVCNKRFSQMY 410
            |.:.::..|.:|  :.|..: |:..|.:||.:...::.|::|||.|||::|::||.|.|.||..:
Zfish   174 KTYFNQHDLNQH--LRDCHSDKKHGCYLCGNEFTRQSSLQKHMRIHTGERPYSCPHCGKTFSYKH 236

  Fly   411 NMKAHLR 417
            :||.|::
Zfish   237 SMKMHVK 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	5/19 (26%)
		C2H2 Zn finger	314..334	CDD:275368	5/19 (26%)
		zf-H2C2_2	327..351	CDD:290200	9/23 (39%)
		C2H2 Zn finger	342..391	CDD:275368	14/49 (29%)
		zf-H2C2_2	383..408	CDD:290200	13/24 (54%)
		C2H2 Zn finger	399..419	CDD:275368	9/19 (47%)
		C2H2 Zn finger	432..449	CDD:275368
si:dkeyp-2e4.2	NP_001122042.1	C2H2 Zn finger	80..100	CDD:275368	5/19 (26%)
		zf-H2C2_2	92..117	CDD:290200	8/27 (30%)
		C2H2 Zn finger	108..128	CDD:275368	5/19 (26%)
		C2H2 Zn finger	141..161	CDD:275368	5/19 (26%)
		C2H2 Zn finger	169..217	CDD:275368	14/49 (29%)
		zf-H2C2_2	209..234	CDD:290200	13/24 (54%)
		C2H2 Zn finger	225..243	CDD:275368	9/17 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100