DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and RGS2

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_014750.3	Gene:	RGS2 / 854274	SGDID:	S000005633	Length:	309	Species:	Saccharomyces cerevisiae

Alignment Length:	163	Identity:	30/163 - (18%)
Similarity:	63/163 - (38%)	Gaps:	32/163 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   340 GAHGYV--YNPSTTNTSYVPNSRVDSERASVSSGGRTDSDTMSISSCSMDGRPYIQRRHSSTESK 402
            |.|.:|  .|....:.:|..|.....:  .:.:...|...::.:...|.|...|:::...:..|.
Yeast   147 GYHRFVSSVNEKKYSATYAHNDSATEQ--DLKNESTTSFSSLGVEDISEDRNSYLKKPDINGLST 209

  Fly   403 AIRQSAMANKETNTFQVIPRTQR--------------LHSNEHRPLKEEELVSL------LIPKL 447
            .|:::: || .||..|...||.|              ..:...|.|::.:...:      |:.||
Yeast   210 IIQETS-AN-TTNESQCSDRTSRPSESSSSLNTTSSTYKNTSTRNLQKPQNTGILNSGKGLLQKL 272

  Fly   448 EEVKRKRDLEERARERNPGAALLTNERSSASDR 480
            ..||:::..::      |...:.::..|:..:|
Yeast   273 NFVKKRKSFKQ------PSGVICSHYNSNVQNR 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
RGS2	NP_014750.3	RGS	42..154	CDD:188659	3/6 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810