DRSC/TRiP Functional Genomics Resources

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Protein Alignment Axn and RGS8

DIOPT Version :9

Sequence 1:NP_733336.1 Gene:Axn / 43565 FlyBaseID:FBgn0026597 Length:745 Species:Drosophila melanogaster
Sequence 2:NP_203131.1 Gene:RGS8 / 85397 HGNCID:16810 Length:198 Species:Homo sapiens


Alignment Length:173 Identity:41/173 - (23%)
Similarity:75/173 - (43%) Gaps:21/173 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 GIRKHDDNECSGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKY 71
            |...|..:.||.....:|.:.:|..|         :.|:.....||.:.:.||..:.||..|:.:
Human    36 GCLSHKSDSCSDFTAILPDKPNRALK---------RLSTEEATRWADSFDVLLSHKYGVAAFRAF 91

  Fly    72 VEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIYRFLR-----KSQLSISDDLRAQIKAIK 131
            ::.|..  .::|.|:.|||..|:.....|   ::...:|...     ::...::.|.:.: :|.:
Human    92 LKTEFS--EENLEFWLACEEFKKTRSTAK---LVSKAHRIFEEFVDVQAPREVNIDFQTR-EATR 150

  Fly   132 TNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQ 174
            .|.:.| |...||..|..|...:..:.||.||.|:||:..:.|
Human   151 KNLQEP-SLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQ 192

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AxnNP_733336.1 RGS 55..170 CDD:295367 30/119 (25%)
Axin_b-cat_bind 494..543 CDD:285982
DIX 665..739 CDD:279160
RGS8NP_203131.1 RGS_RGS8 64..188 CDD:188666 33/130 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3589
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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