DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and SST2

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_013557.1	Gene:	SST2 / 851173	SGDID:	S000004444	Length:	698	Species:	Saccharomyces cerevisiae

Alignment Length:	175	Identity:	41/175 - (23%)
Similarity:	65/175 - (37%)	Gaps:	61/175 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACE 90
            :|.:....:||.:.....|| |.||   .|:::|.|.....||::::|:|....|  |:.:...:
Yeast   396 DEKKTLDDSEGFSQDMLISS-SNLN---KLDYVLTDPGMRYLFRRHLEKELCVEN--LDVFIEIK 454

  Fly    91 G-LKQQT----------------------------DPEKIKQ----------------IIGAIYR 110
            . ||:.|                            |...:||                :||:.|
Yeast   455 RFLKKMTILKKLIDSKHCDKKSNTSTSKNNIVKTIDSALMKQANECLEMAYHIYSSYIMIGSPY- 518

  Fly   111 FLRKSQLSISDDLRAQIKAIKTNPEIPLSPH----IFDPMQRHVE 151
                 ||:|..:||..|..|..:|..|||.|    ::||.....|
Yeast   519 -----QLNIHHNLRQNISDIMLHPHSPLSEHFPTNLYDPSPASAE 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	33/146 (23%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
SST2	NP_013557.1	DEP	57..135	CDD:295306
		DEP_RGS7-like	265..353	CDD:239897
		RGS	420..>537	CDD:295367	25/124 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900