DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Axn and Rgs10

DIOPT Version :9

Sequence 1:NP_733336.1 Gene:Axn / 43565 FlyBaseID:FBgn0026597 Length:745 Species:Drosophila melanogaster
Sequence 2:XP_006508202.1 Gene:Rgs10 / 67865 MGIID:1915115 Length:185 Species:Mus musculus


Alignment Length:141 Identity:36/141 - (25%)
Similarity:70/141 - (49%) Gaps:15/141 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 EGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTD-- 97
            :|.:.:...|..|...||.:|.:||||.:||:.|::::::|..  .:::.|:.|||..|:..|  
Mouse    26 DGSSSSGHQSLKSTAKWASSLENLLEDPEGVQRFREFLKKEFS--EENVLFWLACEDFKKTEDRK 88

  Fly    98 --PEKIKQIIGAIYRFLRKSQLSISDDLRAQIKAIKTNPEIPLSPH--IFDPMQRHVEVTIRDNI 158
              .||.|:|..........||:::....|...|.::       .||  :|..:|..:...::.:.
Mouse    89 QMQEKAKEIYMTFLSNKASSQVNVEGQSRLTEKILE-------EPHPLMFQKLQDQIFNLMKYDS 146

  Fly   159 YPTFLCSEMYI 169
            |..||.|::::
Mouse   147 YSRFLKSDLFL 157

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AxnNP_733336.1 RGS 55..170 CDD:295367 31/121 (26%)
Axin_b-cat_bind 494..543 CDD:285982
DIX 665..739 CDD:279160
Rgs10XP_006508202.1 RGS_RGS10 46..158 CDD:188695 31/121 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3589
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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