DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and Rgs18

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_075019.1	Gene:	Rgs18 / 64214	MGIID:	1927498	Length:	235	Species:	Mus musculus

Alignment Length:	158	Identity:	42/158 - (26%)
Similarity:	74/158 - (46%)	Gaps:	12/158 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLN 84
            ||...||....:...  :|..::.|....:.||.:.:.||..||||:.|.::::.|..  .:::.
Mouse    54 RPDFHGETQASRSAL--LAKETRVSPEEAVKWAESFDKLLSHRDGVDAFTRFLKTEFS--EENIE 114

  Fly    85 FYFACEGLKQQTDPEKIKQIIGAIY-RFLRK---SQLSISDDLRAQIKAIKTNPEIPLSPHIFDP 145
            |:.|||..|:..:|::|.....||| :|::.   .:::|....:..|......|.:    |.||.
Mouse   115 FWVACEDFKKCKEPQQIILKAKAIYEKFIQNDAPKEVNIDFHTKEVIAKSIAQPTL----HSFDT 175

  Fly   146 MQRHVEVTIRDNIYPTFLCSEMYILYIQ 173
            .|..|...:..:.|..||.||.|:..|:
Mouse   176 AQSRVYQLMEHDSYKRFLKSETYLHLIE 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	33/118 (28%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Rgs18	NP_075019.1	RGS	87..199	CDD:295367	32/117 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900