DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and Rgs20

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_001171266.1	Gene:	Rgs20 / 58175	MGIID:	1929866	Length:	372	Species:	Mus musculus

Alignment Length:	154	Identity:	38/154 - (24%)
Similarity:	68/154 - (44%)	Gaps:	23/154 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RPPVPG-EESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHL 83
            |..:|. |||....:.|..|            ||::.::|:....|...|::::..|..  .:::
Mouse   223 RTDIPACEESPTPTLEEVCA------------WAQSFDNLMVTPAGRNAFREFLRTEFS--EENM 273

  Fly    84 NFYFACEGLKQQTDPEKIKQIIGAIYR----FLRKSQLSISDDLRAQIKAIKTNPEIPLSPHIFD 144
            .|:.|||.||::.:...|::....||.    .|...::|:...:|..|.....:|    |.||||
Mouse   274 LFWMACEELKREANKSTIEEKARIIYEDYISILSPKEVSLDSRVREVINRNMVDP----SQHIFD 334

  Fly   145 PMQRHVEVTIRDNIYPTFLCSEMY 168
            ..|..:...:..:.||.|:.|.:|
Mouse   335 DAQLQIYTLMHRDSYPRFMNSTVY 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	29/118 (25%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Rgs20	NP_001171266.1	RGS	205..360	CDD:295367	38/154 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900