DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Axn and rgs4

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_954968.1	Gene:	rgs4 / 569876	ZFINID:	ZDB-GENE-030131-9839	Length:	215	Species:	Danio rerio

Alignment Length:	175	Identity:	42/175 - (24%)
Similarity:	80/175 - (45%)	Gaps:	21/175 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RPPVPGEESRVK-----KMTEGVADTSKNS-SPSYL-NWARTLNHLLEDRDGVELFKKYVEEEAP 77
            :|..|.|:..:|     |..|.|.||..|. :|:.. .|..:..:|:::.||.:.|..:::.|
Zfish    29 KPDPPQEQKALKEKEKEKDKEKVKDTVVNRITPAETEKWKTSFTNLIKNDDGRKAFASFLQSE-- 91

  Fly    78 AYN-DHLNFYFACEGLKQQTDPEKIKQIIGAIY-RFLRKS---QLSISDDLRAQIKAIKTNPEIP 137
             |: :::.|:.|||..| ||..:|:......|: |::...   ::::....|.|   .:.|.|:
Zfish    92 -YSQENIEFWVACEDFK-QTPADKMNLKARNIFERYIEADSPREVNLDSVTREQ---TRKNLEM- 150

  Fly   138 LSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERC 182
            .....||..|..:...:..:.|..||.|.:: |.:.|.:...:.|
Zfish   151 CDVSCFDEAQSKIFTLMEKDSYRRFLRSRLF-LELSQPAMDNKPC 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	27/119 (23%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
rgs4	NP_954968.1	RGS	71..183	CDD:295367	27/120 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900