DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and Rgs19

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_001278134.1	Gene:	Rgs19 / 56470	MGIID:	1915153	Length:	243	Species:	Mus musculus

Alignment Length:	168	Identity:	39/168 - (23%)
Similarity:	66/168 - (39%)	Gaps:	33/168 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 CSGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYN 80
            |....||.|.|..                     :||::.:.|:....|..:|:.::..|   |:
Mouse   100 CEVCTPPSPKEVQ---------------------SWAQSFDKLMHSPTGRSVFRAFLRTE---YS 140

  Fly    81 -DHLNFYFACEGLKQQTDPEKIKQIIGAIYR----FLRKSQLSISDDLRAQIKAIKTNPEIPLSP 140
             :::.|:.|||.||.:.:...:.:....||.    .|...::|:...:|..|......|    ||
Mouse   141 EENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINRKMQEP----SP 201

  Fly   141 HIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQ 178
            |.||..|..:...:..:.||.||.|..|...:.|.:.|
Mouse   202 HTFDDAQLQIYTLMHRDSYPRFLTSPTYRSLLLQGAPQ 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	30/119 (25%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Rgs19	NP_001278134.1	RGS_RGS19	114..231	CDD:188699	32/123 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900