Protein Alignment Axn and grid2ipb

DIOPT Version :9

• Sequence 1: NP_733336.1
• Gene: Axn / 43565
• FlyBaseID: FBgn0026597
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_009304908.1
• Gene: grid2ipb / 559717
• ZFINID: ZDB-GENE-040724-161
• Length: 1383
• Species: Danio rerio
• Alignment Length: 538
• Identity: 108/538 - (20%)
• Similarity: 176/538 - (32%)
• Gaps: 159/538 - (29%)

  Fly   243 GTCSASGSVYGPSTSASSSGSISATDTLPRSSTLPTLHEDSVLSLCDDFEKVQMQEGGGSLGSGS 307
            |..||...|...:...|||..:|.|.           |:::|.....|...:     |..||.|:
Zfish   531 GFKSAEPEVGAETHRRSSSMRVSGTS-----------HKNTVRERSSDDCII-----GTHLGMGT 579

  Fly   308 -----------VGAGARAPD-----------------YPIRLTRDLLIATQKRRLEIRPPGAHGY 344
                       .|.|...|:                 ||::.::.|...:.        |.|.|.
Zfish   580 FTDPVTPEERQCGDGTSFPESPDLSHMTGVYTELGNVYPVKSSQSLQSHSS--------PRAAGM 636

  Fly   345 VYNPSTTNTSYVPNSRVDSERASVS-------SGGRTDSDTMSISS-CSMDGRPYIQRRHSSTES 401
            ....|.|.|....:|...:.::.:|       .|.:.::...:::| .|:|..||:     |.:|
Zfish   637 GLAESNTYTQSFTHSTAGNRKSGLSLTWTDSFPGPQFETYQQTVASPDSVDSNPYV-----SLDS 696

  Fly   402 KAIRQSAMANKETNTFQVIPRTQRLHSNEHRPLKEEELVSLLIPKLEEVKRK-----------RD 455
            ..  .|.:.:.|.:.   :|:.::|.:.. ||.:..:....|....|::..:           .|
Zfish   697 PP--ASPLPSDELSP---LPQRRKLFTFS-RPPRSRDTDKFLDALSEQLGHRVNIVDDFKGGEND 755

  Fly   456 LEERARERNPGAALLTNERSSASDRAFAEAIREKFALDEDNDQDILDQHVSRVWKDQTPHRSPGT 520
            .||.:.:......:|.:|.||||              .||:...  |...|..:...:.|..|..
Zfish   756 YEEMSFQDEQEVNMLPHELSSAS--------------SEDHSSS--DDSTSVSYSSGSDHIPPPP 804

  Fly   521 MSPCPPIPSRRRTATHDSGMVSDGAMSLSGHSMKHSKSMPDHSSCSRKLTNKWPSMNTDSGIS-- 583
            .||.||.|..:.|.       |...:.::          |:|      |....|:......|:
Zfish   805 QSPPPPPPPLQFTD-------SPSPLPIT----------PEH------LPQPPPAFQHHPIIAPP 846

  Fly   584 -----MFSADTVTKYKDASSRSGSSTASKLEEAKRRLEDEPRRSRRYAQPPMQHLSQ--QPLASF 641
                 .|.|:..:.:|...:|          |..|.....||||.  .||..|.:.|  ||.|..
Zfish   847 PPPPRPFLANRPSLHKVLPTR----------EELRAQHSHPRRSS--PQPSSQPILQLHQPKAHP 899

  Fly   642 SSSSSGGSISLPHQPPPLPAKPPETIVVFSFCEEP-----VPYRIKIPGTQPTLRQFKDY--LPR 699
            ...||      ||..|    :||.|....:..:.|     ...:..:|.|.|:|.:.|..  .|.
Zfish   900 ILQSS------PHTSP----QPPHTSAQHTRLQHPSQSIYQSQQTTVPRTSPSLTKQKSLHSQPS 954

  Fly   700 RGHFRFFFKTHCEDPDSP 717
            :..|.....:....|..|
Zfish   955 QQSFEGTLSSKVPPPPPP 972

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367
		Axin_b-cat_bind	494..543	CDD:285982	12/48 (25%)
		DIX	665..739	CDD:279160	11/60 (18%)
grid2ipb	XP_009304908.1	PDZ_signaling	9..69	CDD:238492
		PDZ_signaling	80..156	CDD:238492
		HN_L-delphilin-R1_like	183..262	CDD:259820
		PDZ_signaling	335..410	CDD:238492
		HN_L-delphilin-R2_like	451..530	CDD:259821
		FH2	995..1360	CDD:280362

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900