DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and Rgs7

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_062216.1	Gene:	Rgs7 / 54296	RGDID:	3570	Length:	477	Species:	Rattus norvegicus

Alignment Length:	153	Identity:	41/153 - (26%)
Similarity:	68/153 - (44%)	Gaps:	12/153 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PPVPGEESRVKKMTEGVADTSKNSSPSYL-NWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLN 84
            ||.|.........|....:.||..|...: .|...::..|:|..|.|.|.|::|.|..:.|  |.
  Rat   299 PPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSEN--LR 361

  Fly    85 FYFACEGLKQ---QTDPEKIKQIIGAIYRFLRKSQLS-ISDDLRAQIKAIKTNPEIPLSPHIFDP 145
            |:.|.|.||:   :..|.::::|   ...||.....| |:.|.::..|..: |.:.| ..:.|:.
  Rat   362 FWLAVEDLKKRPIREVPSRVQEI---WQEFLAPGAPSAINLDSKSYDKTTQ-NVKEP-GRYTFED 421

  Fly   146 MQRHVEVTIRDNIYPTFLCSEMY 168
            .|.|:...::.:.||.|:.|..|
  Rat   422 AQEHIYKLMKSDSYPRFIRSSAY 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	33/118 (28%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Rgs7	NP_062216.1	DEP_RGS7-like	29..116	CDD:239897
		RGS_DHEX	113..214	CDD:375589
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	236..257
		GGL	256..316	CDD:128520	4/16 (25%)
		RGS_RGS7	326..446	CDD:188692	34/126 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900