DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and Rgs1

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	XP_006250036.1	Gene:	Rgs1 / 54289	RGDID:	3561	Length:	209	Species:	Rattus norvegicus

Alignment Length:	179	Identity:	47/179 - (26%)
Similarity:	84/179 - (46%)	Gaps:	21/179 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 DDNECSGPRPPVPGEE------SRVKKMTEGV-ADTSKN--SSPSYLNWARTLNHLLEDRDGVEL 67
            |||: ...||...|.:      |.:..:..|: :..||:  |:...:.|:::|..||.::.|..:
  Rat    35 DDNK-QKKRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDILSAEEVMQWSQSLEKLLANQMGQNV 98

  Fly    68 FKKYVEEEAPAYNDHLNFYFACEGLKQ-QTD--PEKIKQIIGAIYRFLRKSQLSISDDLR-AQIK 128
            |.|:::.|..  .:::.|:.|||..|: :||  ..|.:.|..|........|::|....| :..|
  Rat    99 FGKFLKSEFS--EENIEFWLACEDYKKTETDLLHNKAEHIYKAFVHSDAVKQINIDFHTRESTAK 161

  Fly   129 AIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSA 177
            .|||.     :|..||..|:.:...:..:.||.||.|.:|:..:..:.|
  Rat   162 KIKTP-----TPTCFDEAQKVIYALMEKDSYPRFLKSNIYLNLLNDLQA 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	34/118 (29%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Rgs1	XP_006250036.1	RGS	86..199	CDD:413378	34/119 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900