DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and Rgs1

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_056626.2	Gene:	Rgs1 / 50778	MGIID:	1354694	Length:	209	Species:	Mus musculus

Alignment Length:	193	Identity:	47/193 - (24%)
Similarity:	87/193 - (45%)	Gaps:	24/193 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SGHPSGIRKHD----DNECSGPRPPVPGEE------SRVKKMTEGVADT-SKN--SSPSYLNWAR 53
            |..|...::|.    |::....||...|.:      |.:..:..|:... ||:  |:...:.|::
Mouse    20 SASPKDSKEHSHSLLDDKKQKKRPKTFGMDVKTYLRSMIPHLESGMKSAKSKDILSAEEVMQWSQ 84

  Fly    54 TLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQ-QTD--PEKIKQIIGAIYRFLRKS 115
            :|..||.::.|..:|.::::.|..  .:::.|:.|||..|: :||  ..|.:.|..|........
Mouse    85 SLEKLLANQTGQNVFGRFLKSEFS--EENIEFWLACEDYKKTETDLLHNKAENIYKAFVHSDAVK 147

  Fly   116 QLSISDDLR-AQIKAIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSA 177
            |::|....| :..|.|||.     :|..||..|:.:...:..:.||.||.|.:|:..:..:.|
Mouse   148 QINIDFHTRESTAKKIKTP-----TPTSFDEAQKVIYSLMEKDSYPRFLKSNIYLNLLNDLQA 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	33/118 (28%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Rgs1	NP_056626.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..42		4/21 (19%)
Rgs1	NP_056626.2	RGS	86..199	CDD:295367	33/119 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900