DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and rgs8

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_001002531.1	Gene:	rgs8 / 436804	ZFINID:	ZDB-GENE-040718-264	Length:	174	Species:	Danio rerio

Alignment Length:	181	Identity:	40/181 - (22%)
Similarity:	79/181 - (43%)	Gaps:	24/181 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GIRKHDDNECSGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKY 71
            |...:..:.||.....:|..:.|..:..       |.|:.....||.:.:.||.::.|:..|:.:
Zfish     6 GCLSNKSDSCSDFSEFLPPAQERTTRCL-------KLSNDEVTRWADSFDILLSNKYGLAAFRTF 63

  Fly    72 VEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIYR-FL---RKSQLSISDDLRAQIKAIKT 132
            ::.|..  ::::.|:.|||..|:...|.|:......||: |:   ...:::|....|.:.|
Zfish    64 LKTEFS--DENIEFWLACEDYKKIKSPAKMMSKANKIYKEFIDVHAPREVNIDHRTREETK---- 122

  Fly   133 NPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMY-------ILYIQQMS 176
            |..:..:||..:.:|..|...:..:.||.|:.|::|       .:|.|:.|
Zfish   123 NRLLEPTPHSLNEVQAKVYSLMEKDSYPRFIRSKIYQDLLNRTQIYCQRKS 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	28/125 (22%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
rgs8	NP_001002531.1	RGS	36..160	CDD:295367	31/129 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900