DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and Rgs17

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_001100929.1	Gene:	Rgs17 / 308118	RGDID:	1305515	Length:	210	Species:	Rattus norvegicus

Alignment Length:	175	Identity:	37/175 - (21%)
Similarity:	86/175 - (49%)	Gaps:	17/175 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IRKHDDNECSGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYV 72
            :|..:..:.|| |||...:...::.:.|    ....::...|:|::..:.:::...|..||::::
  Rat    43 VRNEERGDSSG-RPPHTTKMESIQVLEE----CQNPTADEVLSWSQNFDKMMKAPAGRNLFREFL 102

  Fly    73 EEEAPAYN-DHLNFYFACEGLKQQTDPEKIKQIIGAIYR----FLRKSQLSISDDLRAQIKAIKT 132
            ..|   |: ::|.|:.|||.||::.:.:.:::....||.    .|...::|:...:|..|.....
  Rat   103 RTE---YSEENLLFWLACEDLKKEQNKKAVEEKARMIYEDYISILSPKEVSLDSRVREVINRNLL 164

  Fly   133 NPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSA 177
            .|    |||:::..|..:...:..:.:|.||.|::|..:::..::
  Rat   165 EP----SPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKAFVESTAS 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	28/119 (24%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Rgs17	NP_001100929.1	RGS	41..197	CDD:413378	36/165 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900