DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and Rgs18

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_001040549.1	Gene:	Rgs18 / 289076	RGDID:	1306522	Length:	235	Species:	Rattus norvegicus

Alignment Length:	154	Identity:	43/154 - (27%)
Similarity:	73/154 - (47%)	Gaps:	4/154 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLN 84
            ||...||....:...  :|..::.||...|.||.:.:.||..||||:.|.::::.|..  .:::.
  Rat    54 RPDFHGETHTSRSAL--LAKETRVSSEEALKWAESFDKLLSHRDGVDAFTRFLKTEFS--EENIE 114

  Fly    85 FYFACEGLKQQTDPEKIKQIIGAIYRFLRKSQLSISDDLRAQIKAIKTNPEIPLSPHIFDPMQRH 149
            |:.|||..|:.|:|:::.....:||....|:......:|....|.:.|......:.|.||..|..
  Rat   115 FWVACEDFKKCTEPQQLILKAKSIYEKFIKNDAPKEVNLDFHTKEVITKSIAQPTLHSFDAAQSR 179

  Fly   150 VEVTIRDNIYPTFLCSEMYILYIQ 173
            |...:..:.|..||.||:|:..|:
  Rat   180 VCQLMEHDSYKRFLKSEIYLHLIE 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	32/114 (28%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Rgs18	NP_001040549.1	RGS	87..199	CDD:295367	31/113 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900