DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and Rgs13

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_694811.1	Gene:	Rgs13 / 246709	MGIID:	2180585	Length:	158	Species:	Mus musculus

Alignment Length:	136	Identity:	34/136 - (25%)
Similarity:	61/136 - (44%)	Gaps:	14/136 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 LNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIYRFLR 113
            |.||::|..|:..:.|..::..|::.|..  ::::.|:.|||..|      ||....|.|.|..:
Mouse    29 LKWAQSLESLMATKYGPIVYTAYLKLEHS--DENIKFWMACETYK------KIASRRGRISRAKK 85

  Fly   114 KSQLSISDDLRAQIKAIKTNPEIPL------SPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYI 172
            ...:.|......:|....|..|..:      :...|:..|:.|.:.:..:.||.||.||||...:
Mouse    86 LYNIYIQPQSPREINIDSTTREAIIKSIREPTQTCFEEAQKIVYMHMEMDSYPRFLKSEMYQQLL 150

  Fly   173 QQMSAQ 178
            :.:.:|
Mouse   151 KTVQSQ 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	30/120 (25%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
Rgs13	NP_694811.1	RGS	36..148	CDD:383028	29/119 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900