Protein Alignment Axn and Rgs2

DIOPT Version :10

• Sequence 1: NP_733336.1
• Gene: Axn / 43565
• FlyBaseID: FBgn0026597
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_033087.2
• Gene: Rgs2 / 19735
• MGIID: 1098271
• Length: 211
• Species: Mus musculus
• Alignment Length: 175
• Identity: 45/175 - (25%)
• Similarity: 74/175 - (42%)
• Gaps: 19/175 - (10%)

  Fly    17 SGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLN-WARTLNHLLEDRDGVELFKKYVEEEAPAYN 80
            |.|..|..|::|:        ..|....||.... ||...:.||..:.|:..|:.:::.|  ...
Mouse    53 SAPGKPKTGKKSK--------QQTFIKPSPEEAQLWAEAFDELLASKYGLAAFRAFLKSE--FCE 107

  Fly    81 DHLNFYFACEGLKQQTDPEKIKQIIGAIYR-FLRK-SQLSISDDLRAQIKAIKTNPEIPLSPHIF 143
            :::.|:.|||..|:...|:|:......||. |:.| :...|:.|.  |.|::........:...|
Mouse   108 ENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDF--QTKSLIAQNIQEATSGCF 170

  Fly   144 DPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERCTSSGAT 188
            ...|:.|...:.:|.||.||.||.|    |.:..:.:..|...||
Mouse   171 TTAQKRVYSLMENNSYPRFLESEFY----QDLCKKPQITTEPHAT 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:470619	31/116 (27%)
		Axin_b-cat_bind	495..530	CDD:462616
		DIX	665..741	CDD:459936
Rgs2	NP_033087.2	Necessary for membrane association. /evidence=ECO:0000250|UniProtKB:P41220	32..66		5/20 (25%)
		Necessary to inhibit protein synthesis. /evidence=ECO:0000250|UniProtKB:P41220	79..116		8/38 (21%)
		RGS_RGS2	84..197	CDD:188664	31/120 (26%)