DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and rgs-4

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_001364555.1	Gene:	rgs-4 / 189666	WormBaseID:	WBGene00004347	Length:	308	Species:	Caenorhabditis elegans

Alignment Length:	200	Identity:	44/200 - (22%)
Similarity:	85/200 - (42%)	Gaps:	20/200 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RKHDDNECSGPRPPVPGEESRVKKMTEGVADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVE 73
            |:.::|:.:|.....|...:.:..::......|...||:  .|....:|::.|.||...|.|:::
Worm   112 RRSNENQSNGNGSTPPTSANNMNMISPNQVPPSPRLSPN--EWQFAFDHVIYDVDGRAQFTKFLQ 174

  Fly    74 EEAPAYN-DHLNFYFACEGLKQQTDPE---KIKQIIGAIY-RFLRKSQ---LSISDDLRAQIKAI 130
            .|   |: :::.|::|.|.||.....|   |.:..:..:| .|:....   ::|..|.|..|.|:
Worm   175 SE---YSEENILFWWAVEELKAVGVSEGRTKFESTVQEMYDTFIAAESPLAINIDHDTRTDIIAL 236

  Fly   131 KTNPEIPLSP-HIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQE------RCTSSGAT 188
            ....|....| :|::..|.||...:..:.:..|:.:..|....:::|..|.      |....|.|
Worm   237 VEGKEPSTFPENIYERAQAHVYRLMEKDCFSRFVHTNAYKDVAKKLSLPQTFRFNCIRLQPGGPT 301

  Fly   189 GSGSA 193
            ...:|
Worm   302 AQAAA 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	30/123 (24%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
rgs-4	NP_001364555.1	RGS	156..277	CDD:214613	30/123 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910