DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and rgs-2

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_001379248.1	Gene:	rgs-2 / 181414	WormBaseID:	WBGene00004345	Length:	181	Species:	Caenorhabditis elegans

Alignment Length:	163	Identity:	45/163 - (27%)
Similarity:	79/163 - (48%)	Gaps:	21/163 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 NECSGPRPPVPGEESRVKKMTEGVADTSKNSSPSY---LNWARTLNHLLEDRDGVELFKKYVEEE 75
            |.....:|.|.|..|..||..|      .:..|:|   ..|:::..:|::.|.|.:.|.::::.|
Worm    18 NSSPSGKPYVSGSVSVEKKNQE------NDGPPTYEIVFGWSQSFENLMKHRAGQKYFAEFLKGE 76

  Fly    76 APAYND-HLNFYFACEGLKQQTDPEKIKQIIGAIYR----FLRKSQLSISDDLRAQIKAIKTNPE 135
               |:| ::.|:.|||.||::.:.|||::....||.    .|...::|:...:|   :.:.||..
Worm    77 ---YSDENILFWQACEELKREKNAEKIEEKARIIYEDFISILSPKEVSLDSRVR---EIVNTNMG 135

  Fly   136 IPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMY 168
            .| |...||..|..:...::.:.||.||.|.:|
Worm   136 RP-SASTFDEAQNQIYTLMQRDSYPRFLASNIY 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	34/119 (29%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
rgs-2	NP_001379248.1	RGS	52..169	CDD:413378	35/123 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910