DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and rgs-9

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_508350.1	Gene:	rgs-9 / 180506	WormBaseID:	WBGene00004352	Length:	235	Species:	Caenorhabditis elegans

Alignment Length:	152	Identity:	27/152 - (17%)
Similarity:	60/152 - (39%)	Gaps:	33/152 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 LNWARTLNHL-LEDRDGVELFKKYVEEEAPAYNDHLNFYFAC---------EGLKQQTDPEKI-- 101
            |:|.::.:.| ..:..|.:|..::::::..  :|:::|:...         .|.|:..:.::|
Worm   101 LSWKKSPHSLAASEYGGSDLLVQFLKQQTS--DDYVDFWLESGEYRWTRTKPGRKRDIEAQRIYD 163

  Fly   102 KQIIGAIYRFLRKSQLSISDDLRAQIKAIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSE 166
            |.:.|...|.:...:           |....:.:.|....:|...|.:|......:.|..||...
Worm   164 KFVYGECPRKIAHLE-----------KMCFVSRQGPTGRDVFICAQAYVGTNFPKDSYKKFLQDP 217

  Fly   167 MYILYIQQMSAQQERCTSSGAT 188
            :|:..:        :..|||||
Worm   218 IYLNLL--------KTVSSGAT 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	20/126 (16%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
rgs-9	NP_508350.1	RGS	106..222	CDD:214613	20/128 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1481971at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820