DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Axn and rgs-1

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_001255056.1	Gene:	rgs-1 / 176415	WormBaseID:	WBGene00004344	Length:	247	Species:	Caenorhabditis elegans

Alignment Length:	240	Identity:	53/240 - (22%)
Similarity:	94/240 - (39%)	Gaps:	39/240 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SRVKKMTEGVADTSKNSSPSYL------NWARTLNHLLEDRDGVELFKKYVEEEAPAYND-HLNF 85
            |.:.:...|.....::..|..|      :|.::.:.|:..:.|.:.|.::::.|   |:| ::.|
Worm     9 SNLGRKYSGTVSPQRSVQPEALSYEMVYSWQQSFDTLMSFKSGQKCFAEFLKSE---YSDENILF 70

  Fly    86 YFACEGLKQQTDPEKIKQIIGAIYR----FLRKSQLSISDDLRAQIKAIKTNPEIPLSPHIFDPM 146
            :.|||.||::.:.||:::....||.    .|...::|:...:|   :.:.||...|......|..
Worm    71 WQACEELKREKNSEKMEEKARIIYEDFISILSPKEVSLDSKVR---EIVNTNMSRPTQNTFEDAQ 132

  Fly   147 QRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERCTSSGATGSGSAGSSGSGGSSLAGACAL-- 209
            .:..::..||: ||.||.|..|          :|...|.|.|.....|.........|....|
Worm   133 HQIYQLMARDS-YPRFLTSIFY----------RETLASFGITEMDIGGDEEKEREQRAERARLNV 186

  Fly   210 PPTTASGKQQLPQLVPPGA---------FINLPVSSVSGPPAGTC 245
            |.|.|.|..:...::....         ||.:..:|.|.....||
Worm   187 PATAAEGSSKDISMISTAVIAVQYFMQKFIQIARTSSSNSFNSTC 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	31/119 (26%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
rgs-1	NP_001255056.1	RGS	38..154	CDD:383028	32/132 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910